Direct coupling of G proteins to ionic channels.
Direct coupling of G proteins to ionic channels.
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G 蛋白与离子通道的直接偶联。
DOI：
10.1101/sqb.1988.053.01.044
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
Birnbaumer,L
中科院分区：
文献类型：
--
作者：
Brown,AM;Yatani,A;Imoto,Y;Kirsch,G;Hamm,H;Codina,J;Mattera,R;Birnbaumer,L
图1. G蛋白在受体介导的离子通道调节中的作用示意图。间接途径是通过膜酶和细胞质第二信使。G，具有结构的信号转导G蛋白，显示为双圆圈以表示单个受体可以与多于一种类型的G蛋白（如G+和G+）相互作用和/或单个G蛋白可以与多于一种效应子系统（如G，与腺苷酸环化酶和Ca** 通道）相互作用的可能性。
Figure 1. Diagram of the role of G proteins in receptormediated regulation of ionic channels. The indirect pathway is via a membrane enzyme and cytoplasmic second messenger. G, signal-transducing G protein with structure ot/3y, is shown as a double circle to denote the possibility that a single receptor may interact with more than one type of G protein (such as G~ and Go) and/or that a single G protein may interact with more than one effector system (such as G, with adenylyl cyclase and the Ca** channel).