Towards an evidence-based model of fear of cancer recurrence for breast cancer survivors.
Towards an evidence-based model of fear of cancer recurrence for breast cancer survivors.
复制标题
迈向基于证据的恐惧乳腺癌幸存者癌症复发的模型。
DOI：
10.1007/s11764-016-0558-z
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发表时间：
2017-02
期刊：
影响因子：
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通讯作者：
Prins JB
中科院分区：
文献类型：
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作者：
Custers JA;Gielissen MF;de Wilt JH;Honkoop A;Smilde TJ;van Spronsen DJ;van der Veld W;van der Graaf WT;Prins JB
为了了解癌症复发恐惧（FCR）的多维机制，并确定潜在的干预目标，重要的是实证检验FCR的理论模型。本研究旨在评估李-琼斯等人的有效性。的FCR模型。共有1205名乳腺癌幸存者被邀请参加这项研究。参与者收到了一份问卷小册子，其中包括人口统计学和心理社会变量（包括FCR）的问卷。数据分析包括中介模型中直接和间接效应的估计。共有460名妇女（38%）参加了这项研究。中位年龄为55.8岁（范围32-87岁）。通过FCR的外部和内部线索的间接影响被发现为所有的中介模型与有限的规划为未来（R 2 = 0.28）和身体检查（R 2 = 0.11 - 0.15）作为行为反应变量，与有限的规划为未来的影响最大。一个直接的关系，发现感觉不舒服，寻求专业意见，而不是介导的FCR。在FCR的第一个测试模型中，所有内部和外部线索都与更高的FCR相关。在有限的未来规划和身体检查的行为反应的模型中，通过FCR线索的间接影响被发现支持Lee-Jones等人的理论模型。FCR的循证模型可能有助于制定适当的干预措施来管理乳腺癌幸存者的FCR。
In order to understand the multidimensional mechanism of fear of cancer recurrence (FCR) and to identify potential targets for interventions, it is important to empirically test the theoretical model of FCR. This study aims at assessing the validity of Lee-Jones et al.’s FCR model. A total of 1205 breast cancer survivors were invited to participate in this study. Participants received a questionnaire booklet including questionnaires on demographics and psychosocial variables including FCR. Data analysis consisted of the estimation of direct and indirect effects in mediator models. A total of 460 women (38 %) participated in the study. Median age was 55.8 years (range 32–87). Indirect effects of external and internal cues via FCR were found for all mediation models with limited planning for the future (R 2 = .28) and body checking (R 2 = .11–.15) as behavioral response variables, with the largest effects for limited planning for the future. A direct relation was found between feeling sick and seeking professional advice, not mediated by FCR. In the first tested models of FCR, all internal and external cues were associated with higher FCR. In the models with limited planning for the future and body checking as behavioral response, an indirect effect of cues via FCR was found supporting the theoretical model of Lee-Jones et al. An evidence-based model of FCR may facilitate the development of appropriate interventions to manage FCR in breast cancer survivors.