Retention in methadone maintenance drug treatment for prescription-type opioid primary users compared to heroin users
Retention in methadone maintenance drug treatment for prescription-type opioid primary users compared to heroin users
复制标题
DOI：
10.1111/j.1360-0443.2009.02538.x
复制
发表时间：
2009-05-01
期刊：
影响因子：
6
通讯作者：
Donovan, Dennis M.
中科院分区：
文献类型：
--
作者：
Banta-Green, Caleb J.;Maynard, Charles;Donovan, Dennis M.
目的评估美沙酮维持治疗的处方型阿片类药物主要（PTOP）用户相比，海洛因用户的保留。设计和参与者进行了回顾性队列研究，以检查12个月的保留使用阿片类药物之间的关联。研究人群包括2004年和2005年在华盛顿州11个非营利美沙酮维持诊所之一住院的成年人（n = 2308）。对治疗机构进行了固定效应的Logistic回归分析。过去30天的阿片类药物使用类型：任何海洛因使用或没有海洛因使用的主要处方阿片类药物。人口统计学，使用的其他药物，自我报告的医疗和精神问题，社会，家庭和法律的问题，公共援助类型和住房稳定性记录在摄入使用一个全面的生物心理社会工具，治疗和评估报告生成工具。结果-被保留在治疗PTOP相比，海洛因使用者不调整其他因素的几率为1.33（95%置信区间[CI]，1.03，1.71）。在最终的逻辑回归模型中，PTOP与海洛因使用者相比的保留几率为1.25（95% CI，0.93，1.67），表明在调整人口统计学、治疗机构、其他药物使用、公共援助类型、医疗、精神病、社会、法律的和家庭因素后，阿片类药物类型的治疗保留没有统计学显著差异。结论PTOP在美沙酮维持治疗机构的治疗效果与海洛因使用者相当。
Aims To assess retention in methadone maintenance treatment for prescription-type opioid primary (PTOP) users compared to heroin users. Design and participants A retrospective cohort study was carried out to examine the association between opiate types used on 12-month retention. The study population consisted of adults admitted to one of 11 not-for-profit methadone maintenance clinics in 2004 and 2005 throughout Washington State (n = 2308). Logistic regression analyses with fixed effects for treatment agencies were conducted. Measurements Opiate use type in past 30 days: any heroin use or primary prescription opioid without heroin use. Demographics, other drugs used, self-reported medical and psychiatric concerns, social, familial and legal issues, public assistance type and housing stability were documented at intake using a comprehensive biopsychosocial instrument, the Treatment and Assessment Reports Generation Tool. Findings The odds of being retained in treatment for PTOP compared to heroin users not adjusting for other factors was 1.33 (95% confidence interval [CI], 1.03, 1.71). In the final logistic regression model the odds of retention for PTOP compared to heroin users was 1.25 (95% CI, 0.93, 1.67), indicating that there was no statistically significant difference in treatment retention by opiate type after adjusting for demographics, treatment agencies, other drug use, public assistance type, medical, psychiatric, social, legal and familial factors. Conclusion The findings of this study suggest that PTOP can be treated at methadone maintenance treatment facilities at least as effectively as heroin users in terms of treatment retention.