Validity of inspiratory and expiratory methods of measuring gas exchange with a computerized system

Validity of inspiratory and expiratory methods of measuring gas exchange with a computerized system
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DOI:
10.1152/jappl.2001.91.1.218
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发表时间:
2001-07-01
影响因子:
3.3
通讯作者:
Parr, BB
Parr, BB
中科院分区:
医学2区
文献类型:
--
作者:
Bassett, DR;Howley, ET;Parr, BB

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使用吸气和呼气方法测量通气量的计算机化代谢系统的准确性在八名男性受试者中进行了评估。在自行车测力计上测量休息时和五个阶段的气体交换。将呼吸速度计放置在吸气侧和呼气侧,以测量吸气侧(点 I 上的(V))和呼气通气量(点 E 上的(V))。该设备连接到两个系统,从单个混合室采样过期的 O-2 和 CO2。同时,标准(Douglas bag,或 DB)方法评估了 E 点上的 (V) 以及呼出气体中 O-2 和 CO2 的分数(FEO2 和 FECO2),以便随后计算 O-2 吸收量(O-2 点上的(V))、CO2 产生量(CO2 点上的(V))和呼吸交换率。这两个系统都能准确测量各种强度的代谢变量。尽管在 FEO2(激发和过期系统)、FECO2(仅过期系统)和 (V) 点 O-2(仅激发系统)方面,DB 和计算机化系统之间存在差异,但差异非常小(FEO2 = 0.0004,FECO2 = -0.0003,(V) 点 O-2 = -0.018 1/min)。因此,使用吸气或呼气配置的计算机化系统可以以比 DB 技术更省时的方式进行极其精确的测量。
The accuracy of a computerized metabolic system, using inspiratory and expiratory methods of measuring ventilation, was assessed in eight male subjects. Gas exchange was measured at rest and during five stages on a cycle ergometer. Pneumotachometers were placed on the inspired and expired side to measure inspired ((V) over dot I) and expired ventilation ((V) over dot E). The devices were connected to two systems sampling expired O-2 and CO2 from a single mixing chamber. Simultaneously, the criterion (Douglas bag, or DB) method assessed (V) over dot E and fractions of O-2 and CO2 in expired gas (FEO2 and FECO2) for subsequent calculation of O-2 uptake ((V) over dot O-2), CO2 production ((V) over dot CO2), and respiratory exchange ratio. Both systems accurately measured metabolic variables over a wide range of intensities. Though differences were found between the DB and computerized systems for FEO2 (both inspired and expired systems), FECO2 (expired system only), and (V) over dot O-2 (inspired system only), the differences were extremely small (FEO2 = 0.0004, FECO2 = -0.0003, (V) over dot O-2 = -0.018 1/min). Thus a computerized system, using inspiratory or expiratory configurations, permits extremely precise measurements to be made in a less time-consuming manner than the DB technique.