High-resolution, wide-field object reconstruction with synthetic aperture Fourier holographic optical microscopy
High-resolution, wide-field object reconstruction with synthetic aperture Fourier holographic optical microscopy
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DOI：
10.1364/oe.17.007873
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发表时间：
2009-05-11
期刊：
影响因子：
3.8
通讯作者：
Sampson, David D.
中科院分区：
文献类型：
--
作者：
Hillman, Timothy R.;Gutzler, Thomas;Sampson, David D.
我们利用合成孔径傅里叶全息显微镜在毫米级视野内分辨微米级微结构。记录了多个全息图，每个全息图记录了样品对象的傅里叶光谱的不同的有限区域。它们被“缝合在一起”以产生合成孔径。低数值孔径(NA)物镜提供了宽广的视场，以及工作距离长、无浸泡液体和廉价、简单的光学系统等额外优势。在该技术的第一次理论处理之后，我们给出了来自环形合成孔径(NA=0.61)的微芯片靶的图像，其面积是单一全息图(NA=0.13)的15倍，它们表现出相应的质量改进。我们证明，如果物体的结构信息集中在那里，则可以从傅立叶空间的有限子区域获得高质量的重建。(C)2009年美国光学学会
We utilize synthetic-aperture Fourier holographic microscopy to resolve micrometer-scale microstructure over millimeter-scale fields of view. Multiple holograms are recorded, each registering a different, limited region of the sample object's Fourier spectrum. They are "stitched together" to generate the synthetic aperture. A low-numerical-aperture (NA) objective lens provides the wide field of view, and the additional advantages of a long working distance, no immersion fluids, and an inexpensive, simple optical system. Following the first theoretical treatment of the technique, we present images of a microchip target derived from an annular synthetic aperture (NA = 0.61) whose area is 15 times that due to a single hologram (NA = 0.13); they exhibit a corresponding qualitative improvement. We demonstrate that a high-quality reconstruction may be obtained from a limited sub-region of Fourier space, if the object's structural information is concentrated there. (C) 2009 Optical Society of America