Chocolate intake is associated with better cognitive function: The Maine-Syracuse Longitudinal Study
Chocolate intake is associated with better cognitive function: The Maine-Syracuse Longitudinal Study
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DOI：
10.1016/j.appet.2016.02.010
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发表时间：
2016-05-01
期刊：
影响因子：
5.4
通讯作者：
Alkerwi, Ala'a
中科院分区：
文献类型：
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作者：
Crichton, Georgina E.;Elias, Merrill F.;Alkerwi, Ala'a
巧克力和可可黄烷醇自古以来就与改善一系列健康问题有关，并已确立了对心血管的好处。关于巧克力对神经认知和行为的影响，人们知之甚少。这项研究的目的是调查巧克力摄入量是否与认知功能有关，并对心血管、生活方式和饮食因素进行调整。对来自缅因州锡拉丘兹纵向研究(MSLS)的968名年龄在23-98岁之间的社区居民进行了横断面分析。通过一系列神经心理测试来衡量，巧克力的习惯性摄入量与认知表现有关。更频繁地食用巧克力与在全球综合得分、视觉空间记忆和组织、工作记忆、扫描和跟踪、抽象推理和Mini-Mini-State检查中的更好表现显著相关。除了工作记忆，这些关系在心血管、生活方式和饮食因素的统计控制下并未减弱。前瞻性分析显示，认知功能与长达18年后的巧克力摄入量之间没有关联。需要进一步的干预试验和纵向研究，以探索巧克力、可可黄烷醇和认知之间的关系，以及潜在的原因机制。(C)2016爱思唯尔有限公司。保留所有权利。
Chocolate and cocoa flavanols have been associated with improvements in a range of health complaints dating from ancient times, and has established cardiovascular benefits. Less is known about the effects of chocolate on neurocognition and behaviour. The aim of this study was to investigate whether chocolate intake was associated with cognitive function, with adjustment for cardiovascular, lifestyle and dietary factors. Cross-sectional analyses were undertaken on 968 community-dwelling participants, aged 23-98 years, from the Maine-Syracuse Longitudinal Study (MSLS). Habitual chocolate intake was related to cognitive performance, measured with an extensive battery of neuropsychological tests. More frequent chocolate consumption was significantly associated with better performance on the Global Composite score, Visual-Spatial Memory and Organization, Working Memory, Scanning and Tracking, Abstract Reasoning, and the Mini-Mental State Examination. With the exception of Working Memory, these relations were not attenuated with statistical control for cardiovascular, lifestyle and dietary factors. Prospective analyses revealed no association between cognitive function and chocolate intake measured up to 18 years later. Further intervention trials and longitudinal studies are needed to explore relations between chocolate, cocoa flavanols and cognition, and the underlying causal mechanisms. (C) 2016 Elsevier Ltd. All rights reserved.