Percutaneous MRI-guided laser-induced thermotherapy for hepatic metastases for colorectal cancer
Percutaneous MRI-guided laser-induced thermotherapy for hepatic metastases for colorectal cancer
复制标题
经皮 MRI 引导激光诱导热疗治疗结直肠癌肝转移
DOI：
10.1016/s0140-6736(97)24027-4
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
R. Felix
中科院分区：
文献类型：
--
作者：
T. Vogl;M. Mack;R. Straub;A. Roggan;R. Felix
Thomas J Vogl, Martin G Mack, Ralf Straub, André Roggan, R Felix procedure. LITT was done after agreement from the local ethics committee and with the patients’ informed consent. All patients tolerated the procedure well; six had mild nausea and a symptomless right subphrenic haemorrhage developed in one. No deaths, infections, or liver or bile-duct injury occurred. During follow-up, 23 of 99 treated patients died: one of myocardial infarction, one from a stroke, 13 from tumour progression in the liver, and eight from tumour progression in other locations. The cumulative survival rate was 0· 88 after 12 months, 0· 70 after 24 months, and 0· 42 after 36 months. Median survival time, calculated by the Kaplan-Meier method, was 36· 4 months (figure). In patients with liver metastases of colorectal cancer, local tumour destruction with LITT under local anaesthesia is well tolerated and results in improved clinical outcome and survival. Our data can be a basis for a randomised comparison of LITT versus surgery.
