Contributions from both the brain and the vascular network guide behavior in the colonial tunicate Botryllus schlosseri.
Contributions from both the brain and the vascular network guide behavior in the colonial tunicate Botryllus schlosseri.
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DOI：
10.1242/jeb.244491
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发表时间：
2022-11-15
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影响因子：
--
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中科院分区：
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We studied the function, development and aging of the adult nervous system in the colonial tunicate Botryllus schlosseri. Adults, termed zooids, are filter-feeding individuals. Sister zooids group together to form modules, and modules, in turn, are linked by a shared vascular network to form a well-integrated colony. Zooids undergo a weekly cycle of regression and renewal during which mature zooids are replaced by developing buds. The zooid brain matures and degenerates on this 7-day cycle. We used focal extracellular recording and video imaging to explore brain activity in the context of development and degeneration and to examine the contributions of the nervous system and vascular network to behavior. Recordings from the brain revealed complex firing patterns arising both spontaneously and in response to stimulation. Neural activity increases as the brain matures and declines thereafter. Motor behavior follows the identical time course. The behavior of each zooid is guided predominantly by its individual brain, but sister zooids can also exhibit synchronous motor behavior. The vascular network also generates action potentials that are largely independent of neural activity. In addition, the entire vascular network undergoes slow rhythmic contractions that appear to arise from processes endogenous to vascular epithelial cells. We found that neurons in the brain and cells of the vascular network both express multiple genes for voltage-gated Na+ and Ca2+ ion channels homologous (based on sequence) to mammalian ion channel genes. In the colonial tunicate Botryllus schlosseri, both the nervous systems of zooids and the excitable vasculature contribute to generating behavior. Both tissues produce patterned output and both express voltage-dependent Na+ and Ca2+ ion channels.
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影响因子：
7.7
作者：
Voskoboynik A;Neff NF;Sahoo D;Newman AM;Pushkarev D;Koh W;Passarelli B;Fan HC;Mantalas GL;Palmeri KJ;Ishizuka KJ;Gissi C;Griggio F;Ben-Shlomo R;Corey DM;Penland L;White RA 3rd;Weissman IL;Quake SR
通讯作者：
Quake SR
影响因子：
64.8
作者：
Delsuc, F;Brinkmann, H;Philippe, H
通讯作者：
Philippe, H
DOI：
10.1007/bf00610225
发表时间：
1987-01-01
影响因子：
2.1
作者：
ARKETT, SA
通讯作者：
ARKETT, SA
影响因子：
0.9
作者：
Ballarin, Loriano;Schiavon, Filippo;Manni, Lucia
通讯作者：
Manni, Lucia
DOI：
10.1111/jzs.12246
发表时间：
2019-05-01
影响因子：
1.9
作者：
Braun, Katrin;Stach, Thomas
通讯作者：
Stach, Thomas