Lacunar infarct
Lacunar infarct
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DOI：
10.1080/10641960600549082
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发表时间：
2006-04-01
影响因子：
12.3
通讯作者：
Lastella, M
中科院分区：
文献类型：
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作者：
Lastella, M
腔隙或脑梗死是指一个明确的皮层下缺血性病变，位于单个穿通动脉水平，由后者的原发病决定。放射学图像显示为小而深的梗死灶。经历这些改变的动脉是深动脉或穿通动脉，直径在100和400 μ m之间，编号为6-12，通常直接从主动脉以直角起源。腔隙综合征的概念是在临床实践中引入的，以描述那些临床表现，一般。虽然不总是，但有腔隙性脑梗死的潜在机制。腔隙性脑梗死引起的典型临床综合征按发生频率降序排列为纯运动性脑卒中、纯感觉性脑卒中、感觉运动性脑卒中。共济失调性轻偏瘫和构音障碍伴单手运动障碍，以及一些罕见或不完全综合征。小的腔隙性梗死，然后将退化成腔隙引起41，减少血流到穿通动脉。反过来，这是各种动脉疾病的结果，其中最常见的包括微动脉粥样硬化、脂透明质变性、纤维素样坏死和夏-布二氏动脉瘤。其他影响小血管的动脉病包括淀粉样血管病和伴有皮质下梗死和白质脑病的脑自体显性动脉病。血液动力学紊乱也被称为是疾病的原因之一。用1.5特斯拉MRI进行诊断，预后一般良好。
The term lacuna, or cerebral infarct, refers to a well-defined, subcortical ischemic lesion at the level of a single perforating artery, determined by primary disease of the latter. The radiological image is that of a small, deep infarct. Arteries undergoing these alterations are deep or perforating arteries with a diameter ranging between 100 and 400 mu m, numbering 6-12, that generally originate at right angles directly from the main arteries. The concept of lacunar syndrome was introduced in clinical practice to describe those clinical pictures that generally. although not always, have a cerebral infarct of lacunar hype as the underlying mechanism. Classic clinical syndromes induced by lacunar infarcts are, in decreasing order of frequency, pure motor stroke, pure sensory stroke, sensorimotor stroke. ataxic hemiparesis, and dysarthria with motor disability of one hand, as well as a number of rare or incomplete syndromes. Small lacunar infarct that will then degenerate into a lacuna is caused 41, a reduction of blood flow to a perforating artery. In turn, this is the result of various arterial disorders, the most frequent of which include microatheroma, lipohyalinosis, fibrinoid necrosis, and Charcot-Bouchard aneurysm. Other forms of arteriopathy that can affect small vessels include amyloid angiopathy, and cerebral autosomic dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Hemodynamic disorders also call be a cause of the disease. Diagnosis is made with 1, 5 Tesla MRI and prognosis is generally good.