Fatal pancreatitis associated with systemic amyloidosis in a rheumatoid arthritis patient.
Fatal pancreatitis associated with systemic amyloidosis in a rheumatoid arthritis patient.
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类风湿性关节炎患者的致命性胰腺炎与系统性淀粉样变性相关。
DOI：
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
Hirofumi Makino
中科院分区：
文献类型：
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作者：
Kazuhiro Oishi;Jun Wada;Y. Nagake;K. Hida;Hiroo Hashimoto;Nobuaki Hayakawa;Naoki Kashihara;Hirofumi Makino
我们在此报告一位69岁的类风湿性关节炎（RA）患者并发全身性AA淀粉样变性的重症急性胰腺炎病例。AA淀粉样蛋白沉积在胰腺小动脉和小动脉壁上。急性胰腺炎对各种干预措施抵抗，发生急性坏死性胰腺炎和多器官功能衰竭。虽然类风湿性关节炎的淀粉样变性很少并发急性胰腺炎，但这种情况下的急性胰腺炎可能是严重和难治性的，并可能导致致命的结局。
We report here a case of severe acute pancreatitis associated with systemic AA amyloidosis in a 69-year-old rheumatoid arthritis (RA) patient. AA amyloid deposition was detected on the walls of small pancreatic arteries and arterioles. The acute pancreatitis was resistant to various interventions, and acute necrotizing pancreatitis and multiple organ failure developed. Although AA amyloidosis in RA patients is rarely complicated with acute pancreatitis, acute pancreatitis in such cases could be severe and intractable and might result in a fatal outcome.