Stage-specific inhibin secretion by rat seminiferous tubules.

Stage-specific inhibin secretion by rat seminiferous tubules.
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大鼠生精小管的阶段特异性抑制素分泌。

DOI:
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发表时间:
1989
期刊:
Reproduction, Fertility and Development
影响因子:
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通讯作者:
D. D. de Kretser
D. D. de Kretser
中科院分区:
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文献类型:
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作者:
G. Gonzales;G. Risbridger;Y. Hodgson;P. Pöllänen;D. D. de Kretser

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如Parvinen(1982)所述,通过放射免疫测定法测定了通过透照辅助解剖分离的生精周期特定阶段的曲细精管节段中的内源性曲细精蛋白含量。此外,研究了响应FSH刺激的免疫活性的Escherichin产生。在周期的第二-第六阶段,肾小管中的Escherichin含量最高,在第七-第八阶段最低。在48小时的培养中,分泌到培养基中的白藜芦醇在第XIII-VI阶段最大,在第VII-VIII阶段最低。卵泡刺激素对FSH刺激的反应在IX-XIII期最大,在VII-VIII期最小。结果表明,在体外的成年小管分泌的曲细精蛋白根据生精周期的阶段而变化。
The endogenous inhibin content was measured by radioimmunoassay in segments of seminiferous tubules at specific stages of the spermatogenic cycle isolated by transillumination-assisted dissection as described by Parvinen (1982). In addition, the immunoactive inhibin production in response to FSH stimulation was investigated. The inhibin content was greatest in tubules at stages II-VI of the cycle and was lowest at stages VII-VIII. Over 48 h of culture, the secretion of inhibin into the medium was greatest at stages XIII-VI and lowest at stages VII-VIII. The inhibin response to FSH stimulation was greatest at stages IX-XIII and least at stages VII-VIII. The results demonstrate that the secretion of inhibin by adult tubules in vitro varies according to the stage of the seminiferous cycle.
DOI: 10.1210/endo-122-2-717
发表时间: 1988-02
期刊: Endocrinology
影响因子: 4.8
作者:
PATRICIA L. Morris;W. Vale;Scott Cappel;C. W. Bardin
通讯作者: PATRICIA L. Morris;W. Vale;Scott Cappel;C. W. Bardin