SOURCES OF SUBCORTICAL GABAERGIC PROJECTIONS TO THE SUPERIOR COLLICULUS IN THE CAT
SOURCES OF SUBCORTICAL GABAERGIC PROJECTIONS TO THE SUPERIOR COLLICULUS IN THE CAT
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DOI：
10.1002/cne.903020111
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发表时间：
1990-12-01
影响因子：
2.5
通讯作者：
BEHAN, M
中科院分区：
文献类型：
--
作者：
APPELL, PP;BEHAN, M
本研究的目的是从猫的尾侧间脑、中脑、脑桥和延髓的神经元识别GABA能传入猫上丘。用辣根过氧化物酶逆行标记上丘传出细胞，用γ-氨基丁酸抗体标记同一切片中的GABA能神经元。结果表明，在尾侧间脑和脑干的几个不同区域的神经元都被免疫细胞化学标记为GABA，并被辣根过氧化物酶逆行标记。这些区域包括未定带、后连合核、顶盖前前核和顶盖后核、视束核、上丘、楔形核、楔下区、黑质网状部和外侧部、腹股沟周围区、内丘外核、下丘外核腹侧区、中脑网状结构、外侧丘脑背侧和腹侧核、舌下神经周围核。这种不同的抑制输入上丘可能发挥的作用，特别是在影响眼睛的运动，进行了讨论。
The goal of this study was to identify GABAergic input to the cat superior colliculus from neurons located in the caudal diencephalon, mesencephalon, pons and medulla. Cells efferent to the superior colliculus were labeled retrogradely with the tracer horseradish peroxidase, and an antibody to gamma-aminobutyric acid was used to label GABAergic neurons in the same sections. The results indicate that neurons in several distinct areas of the caudal diencephalon and brainstem are both immunocytochemically labeled for GABA and retrogradely labeled with horseradish peroxidase. These areas include zona incerta, nucleus of the posterior commissure, anterior and posterior pretectal nuclei, nucleus of the optic tract, superior colliculus, cuneiform nucleus, subcuneiform area, substantia nigra pars retticulata and pars lateralis, periparabigeminal area, external nucleus of the interior colliculus, the area ventral to the external nucleus of the inferior colliculus, mesencephalic reticular formation, dorsal and ventral nuclei of the lateral lemniscus, and the perihypoglossal nucleus. The role that such diverse inhibitory input to the superior colliculus might play, particularly in influencing eye movements, is discussed.