Recovery of Candida dubliniensis and other yeasts from human immunodeficiency virus-associated periodontal lesions
Recovery of Candida dubliniensis and other yeasts from human immunodeficiency virus-associated periodontal lesions
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DOI：
10.1128/jcm.39.12.4520-4522.2001
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发表时间：
2001-12-01
影响因子：
9.4
通讯作者：
Meiller, TF
中科院分区：
文献类型：
--
作者：
Jabra-Rizk, MA;Ferreira, SMS;Meiller, TF
从54名人类免疫缺陷病毒（HIV）阳性和20名HIV阴性患者的牙周病变的口腔和龈下样本收集和培养酵母菌。从HIV阳性患者培养的54个样本中，44个（82%）为酵母菌阳性，其中29个（66%）为龈下。共有19例（48%）患者为都柏林念珠菌阳性，其中15例（79%）在龈下部位定植。回收了7株光滑念珠菌、2株近平滑念珠菌和1株酿酒酵母。本研究报告首次从龈下口内部位回收都柏林念珠菌，并证实了与HIV相关的牙周病部位存在念珠菌。
Oral and subgingival samples from periodontal lesions were collected from 54 human immunodeficiency virus (HIV)-positive and 20 HIV-negative patients and cultured for yeast species. Of the 54 samples cultured from HIV-positive patients, 44 (82%) were positive for yeast species, of which 29 (66%) were subgingival. A total of 19 (48%) patients were positive for Candida dubliniensis, of which 15 (79%) were colonized in subgingival sites. Seven isolates of Candida glabrata, two isolates of Candida parapsilosis, and one isolate of Saccharomyces cerevisiae were recovered. This study reports for the first time the recovery of C dubliniensis from subgingival intraoral sites and confirms the presence of Candida species in sites of periodontal disease associated with HIV.