Activity of single action potentials in monkey motor cortex during long-term task learning

Activity of single action potentials in monkey motor cortex during long-term task learning
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DOI:
10.1016/s0006-8993(97)00051-6
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发表时间:
1997-06-20
期刊:
影响因子:
2.9
通讯作者:
Bakay, RAE
Bakay, RAE
中科院分区:
医学3区
文献类型:
--
作者:
Kennedy, PR;Bakay, RAE

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现在,通过植入神经营养电极,可以在长期学习过程中连续记录神经活动进行研究。在记录猴子执行伸手和抓握任务的个体皮质动作电位时,我们能够跟踪学习任务时几个动作电位放电的逐渐变化。对照实验表明参与学习的神经元最初是沉默的。
Studies using continuous recording of neural activity during long-term learning are now possible with an implanted neurotrophic electrode. During recording of individual cortical action potentials in monkeys performing a reach and grasp task, we were able to follow the gradual change in firing of several action potentials as the task was learned. Control experiments suggest that the neurons involved in the learning were initially silent.