Therapeutic trials in Alzheimer's disease.
Therapeutic trials in Alzheimer's disease.
复制标题
阿尔茨海默病的治疗试验。
作者：
P. Whitehouse;J. Voci
在过去一年中，阿尔茨海默病的治疗试验活动有所增加，新的对症治疗研究开始并继续进行，旨在证明认知能力的增强。对非认知或行为症状干预的兴趣也有所增加。将新的基础科学发现转化为减缓疾病进展的临床方法的尝试也产生了热情。及时考虑某些关键的方法，伦理和政策问题可能会在未来几年加强药物开发的后期活动。
Therapeutic trials activity in Alzheimer's disease increased during the past year, with both the initiation of new and the continuation of ongoing symptomatic treatment studies designed to demonstrate enhancement of cognitive abilities. Interest in interventions for noncognitive or behavioral symptoms has also increased. Attempts to convert new basic scientific discoveries into clinical approaches that slow the progression of the disease also generated enthusiasm. Timely consideration of certain critical methodological, ethical, and policy issues are likely to enhance this late phase activity in drug development in the years to come.