ROLE OF TVB LOCUS IN GENETIC RESISTANCE TO RSV(RAV-O)
ROLE OF TVB LOCUS IN GENETIC RESISTANCE TO RSV(RAV-O)
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DOI：
10.1016/0042-6822(75)90434-1
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发表时间：
1975-01-01
期刊：
影响因子：
3.7
通讯作者：
MOTTA, JV
中科院分区：
文献类型：
--
作者：
CRITTENDEN, LB;MOTTA, JV
在两组自交系鸡中研究了RSV（rv -0）的遗传易感性。RSV是一种属于e亚群的禽肉瘤病毒。来自Reaseheath细胞系的数据表明，一种独立于对B亚群易感性的隐性基因控制了对E亚群病毒的抗性。这一基因被认为是一种新病毒。对区域家禽研究实验室（RPRL）的研究表明，抗性的隐性基因位于tvblous，因此与对B亚群病毒的抗性有遗传联系。测定了RPRL系和Reaseheath系的杂交和回交对绒毛尿囊膜上RSV（rv -0）和RSV（rv -2）的敏感性。这些数据完全支持单一基因座控制对B和E亚群病毒的隐性抗性的假设。因此，没有证据表明它是独立的。
Genetic susceptibility to RSV(RAV-0), an avian sarcoma virus belonging to subgroup E. has been studied in two sets of inbred chicken lines. Data from the Reaseheath lines suggested that a recessive gene, independent of susceptibility to subgroup B, controlled resistance to subgroup E virus. This gene was assumed to be a newtvelocus. Studies of the Regional Poultry Research Laboratory (RPRL) lines suggested that a recessive gene for resistance was located at thetvblocus and thus genetically linked to resistance to subgroup B virus. Crosses and backcrosses of Reaseheath and RPRL lines were assayed for susceptibility to RSV(RAV-0) and RSV(RAV-2) on the chorioallantoic membrane. The data completely support the hypothesis that a single locus controls recessive resistance to subgroup B and E viruses. Therefore, there was no evidence for an independenttvelocus.