Noninvasive localization of accessory pathways by magnetocardiographic imaging
Noninvasive localization of accessory pathways by magnetocardiographic imaging
复制标题
通过心磁图无创定位旁路
作者：
M. Nomura;Y. Nakaya;Ken Saito;F. Kishi;Tetsuzo Watatsuki;H. Miyoshi;A. Nishikado;S. Bando;S. Ito;Hiromu Nlshltanl;M. Wada;S. Fujita;I. Tamura
心磁图（MCG）是一种有助于定位心脏电流源的新方法。为了测试7通道生物磁系统定位早期心室去极化部位的临床准确性，在射频屏蔽室中记录了14例Wolff - Parkinson - White （WPW）综合征患者的mcg。通过标准12导联心电图（ECGs）和体表等电位图对早期心室去极化部位进行分类。3例WPW综合征副通路位于右侧游离壁，11例位于左侧游离壁。用最小二乘法从QRS复合物开始每2 ms计算一次三维（3 - D）偶极子位置。这些三维偶极子位置被投影到门控磁共振图像上，以便可视化计算出的心室源的传播。结果与体表等电位图、心电图和电生理研究结果进行了比较。14例WPW综合征患者中有12例在20 ms时推断出的电流偶极子位置与体表映射的副通路位置具有良好的相关性。MCG能够以无创的方式精确地确定电流源的三维位置，并且可能在导管消融治疗WPW综合征中具有潜在的益处。
The magnetocardiogram (MCG) is a newly developed method that helps localize a cardiac current source. To test the clinical accuracy of a 7‐channel biomagnetic system in the localization of early ventricular depolarization sites, the MCGs of 14 patients with Wolff‐Parkinson‐White (WPW) syndrome were recorded in a radiofrequency‐shielded room. The locations of early ventricular depolarization sites were classified by standard 12‐lead electrocardiograms (ECGs) and body surface iso‐potential mapping. The accessory pathways of 3 patients with WPW syndrome were located in the right free wall and in 11 patients in the left free wall. The three‐dimensional (3‐D) dipole location was computed every 2 ms from the onset of the QRS complex by the least‐square method. These 3‐D dipole locations were projected onto a gated magnetic resonance image in order to visualize the propagation of the calculated ventricular source. The results were compared with those obtained by body surface isopotential mapping, and electrocardiographic and electrophysiologic studies. The location of the deduced current dipole at 20 ms correlated well with the location of the accessory pathway by the body surface mappings in 12 of the 14 patients with WPW syndrome. The MCG is capable of precisely determining the 3‐D location of a current source in a noninvasive manner and may be of potential benefit in the treatment of WPW syndrome by catheter ablation.
影响因子：
158.5
作者：
JACKMAN, WM;WANG, XZ;LAZZARA, R
通讯作者：
LAZZARA, R