An improved urine collection pad method: a randomised clinical trial
An improved urine collection pad method: a randomised clinical trial
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DOI：
10.1136/adc.2003.037770
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发表时间：
2004-08-01
影响因子：
5.2
通讯作者：
Macfarlane, P
中科院分区：
文献类型：
--
作者：
Rao, S;Bhatt, J;Macfarlane, P
目的：评价一种改进的尿路收集垫(UCP)方法减少疑似尿路感染(UTI)患儿尿路标本中重混合细菌污染的能力。方法：将2岁以下发热儿童随机分为两组：保留尿布直到排尿的相同UCP(单一UCP组)，或每30分钟更换一次新的UCP直到排尿(替代UCP组)。结果：共纳入80例患儿，其中68例获得满意的尿样，其中单纯UCP组37例，更换UCP组31例。在12名儿童(15%)中，收集失败，主要是因为粪便污染了垫子。发生尿路感染3例(4%)。在剩余的65个样本中，替换的UCP组有1/31(3%)出现重度混合生长(10(5)个生物体/ml)，而单一UCP组有10/35(29%)(p=0.008)。结论：每隔30分钟更换一次UCP几乎消除了UCP标本严重的混合生长污染，大大增加了UCP结果中有信心排除UTI的比例。这是对UCP方法的简单而重要的改进，UCP方法对于诊断和排除仍在尿布中的儿童尿路感染是可靠的。它具有在门诊、初级保健环境或家庭中使用的潜力。
Aim: To evaluate a modified urine collection pad (UCP) method for its ability to reduce heavy mixed growth bacterial contamination of UCP samples in young children with suspected urinary tract infection (UTI).Method: Febrile children under 2 years of age were randomised to two UCP methods: the same UCP kept in the nappy until urine was passed (single UCP group), or the UCP replaced with a fresh one every 30 minutes until urine was passed (replaced UCP group). In both groups a moisture sensitive audio alarm was used to signal passage of urine.Results: Eighty children were enrolled and a satisfactory sample was obtained in 68 (37 in the single UCP group and 31 in the replaced UCP group). In 12 children (15%), collection failed, mainly because of faecal soiling of the pad. UTI occurred in three children (4%). In the remaining 65 samples, heavy mixed growth (> 10(5) organisms/ml) occurred in 1/31 (3%) in the replaced UCP group compared with 10/35 (29%) in the single UCP group (p = 0.008). There were no adverse effects from the use of the moisture sensitive audio alarm.Conclusion: Changing the UCP every 30 minutes almost eliminates heavy mixed growth contamination of UCP samples and substantially increases the proportion of UCP results that confidently exclude UTI. This represents a simple and clinically important improvement to the UCP method which is reliable for diagnosing and excluding UTI in young children still in nappies. It has potential for use in outpatient clinics, in the primary healthcare setting, or at home.