Renal angiomyolipoma: Relationships between tumor size, aneurysm formation, and rupture
Renal angiomyolipoma: Relationships between tumor size, aneurysm formation, and rupture
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DOI：
10.1148/radiol.2251011477
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发表时间：
2002-10-01
期刊：
影响因子：
19.7
通讯作者：
Takeda, K
中科院分区：
文献类型：
--
作者：
Yamakado, K;Tanaka, N;Takeda, K
目得：评估肿瘤大小，动脉瘤形成和自发性破裂在肾angiomyolipoma.MATERIALS和METHODS：23例肾angiomyolipoma. CT血管造影和检查之间的关系。评价了每个肾脏中的单个最大病变。在CT上测量肿瘤大小，在肾血管造影术上测量动脉瘤大小。比较血管平滑肌脂肪瘤破裂组和未破裂组的肿瘤和动脉瘤大小。多元回归分析，以确定影响破裂的因素。结果：29肾血管平滑肌脂肪瘤确定。8例血管平滑肌脂肪瘤为出血性;其余21例为非出血性。在所有出血性病变中，肿瘤大小大于4 cm，动脉瘤大小为5 mm或更大。破裂和未破裂肿瘤组之间的平均肿瘤大小（11.4 cm +/- 5.5 [SD] vs 5.0 cm +/- 3.1，P <0.02）和平均动脉瘤大小（13.3 mm +/- 6.2 vs 2.4 mm +/- 2.9，P <0.02）存在显著差异。当肿瘤大小为4 cm或更大和动脉瘤大小为5 mm或更大作为破裂的预测因素时，前者的敏感性和特异性分别为100%和38%，后者为100%和86%。多元回归分析表明，动脉瘤的大小是最重要的因素与rupture.CONCLUSION：动脉瘤的形成似乎与肿瘤的大小，和大动脉瘤赋予更高的概率破裂。(C)RSNA，2002年。
PURPOSE: To evaluate the relationships between tumor size, aneurysm formation, and spontaneous rupture in renal angiomyolipomas.MATERIALS AND METHODS: Twenty-three patients with renal angiomyolipoma were examined with angiography and computed tomography (CT). The single largest lesion in each kidney was evaluated. Tumor size was measured at CT, and aneurysm size was measured at renal angiography. Tumor and aneurysm sizes were compared between the group with ruptured angiomyolipoma and the group with unruptured angiomyolipoma. Multiple regression analysis was performed to identify factors affecting rupture.RESULTS: Twenty-nine kidneys with angiomyolipoma were identified. Eight angiomyolipomas were hemorrhagic; the remaining 21 were not hemorrhagic. Tumor size was larger than 4 cm and aneurysm size was 5 mm or larger in all hemorrhagic lesions. There were significant differences in mean tumor size (11.4 cm +/- 5.5 [SD] vs 5.0 cm +/- 3.1, P < .02) and mean aneurysm size (13.3 mm +/- 6.2 vs 2.4 mm +/- 2.9, P < .02) between the ruptured and unruptured tumor groups. When tumor size of 4 cm or larger and aneurysm size of 5 mm or larger were used as predictors of rupture, sensitivity and specificity, respectively, were 100% and 38% with the former criterion and 100% and 86% with the latter criterion. Multiple regression analysis indicated that aneurysm size was the most important factor linked to rupture.CONCLUSION: Aneurysm formation appears to be related to tumor size, and large aneurysms confer a higher probability of rupture. (C) RSNA, 2002.