Novel phospholipids with aliphatic dicarboxylic acid residues in a lipid extract from bovine brain.

Novel phospholipids with aliphatic dicarboxylic acid residues in a lipid extract from bovine brain.
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牛脑脂质提取物中含有脂肪族二羧酸残基的新型磷脂。

DOI:
10.1016/s0006-291x(88)80575-8
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发表时间:
1988
影响因子:
3.1
通讯作者:
H. Tsukatani
H. Tsukatani
中科院分区:
生物学4区
文献类型:
--
作者:
A. Tokumura;T. Asai;K. Takauchi;K. Kamiyasu;T. Ogawa;H. Tsukatani

文献摘要

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从牛脑的脂质提取物中纯化的血管抑制剂磷脂组分被发现含有具有长链酰基和脂肪族二羧酸残基的新型磷脂。这通过用磷脂酶C水解后通过毛细管GC-MS分析甘油酯的叔丁基二甲基甲硅烷基衍生物级分来显示。检测到六种分子物质,其中棕榈酰基和脂肪族二羧酸酯(链长C4-C9),以及两种物质,其中硬脂酰基和琥珀酸酯或戊二酸酯残基。
A vasodepressor phospholipid fraction purified from a lipid extract of bovine brain was found to contain novel phospholipids with both a long-chain acyl group and an aliphatic dicarboxylic acid residue. This was shown by analyzing the fraction astert-butyldimethylsilyl derivatives of glyceride by capillary GC-MS after hydrolysis with phospholipase C. Six molecular species with a palmitoyl group and an aliphatic dicarboxylate(chain length C4-C9), and two species with both a stearoyl group and a succinate or glutarate residue were detected.