Pregnancy, nutrition and parasitic diseases
Pregnancy, nutrition and parasitic diseases
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DOI：
10.1093/jn/133.5.1661s
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发表时间：
2003-05-01
影响因子：
4.2
通讯作者：
Steketee, RW
中科院分区：
文献类型：
--
作者：
Steketee, RW
在发展中国家，年轻妇女、孕妇及其婴儿和儿童经常经历营养不良（常量营养素和微量营养素）和反复感染（包括寄生虫感染）的循环，导致不良后果，并可能从一代人延续到下一代。在寄生虫感染中，疟疾和肠道蠕虫与微量营养素缺乏广泛共存，并在很大程度上导致贫血和生长发育迟缓的循环。在较为有限或集中的地理环境中，其他寄生虫病（例如血吸虫病、丝虫病）对这一循环也有类似的贡献。毫无疑问，在没有感染和营养充足的情况下进入妊娠期比各种替代方案要好得多。应遵循现有的微量营养素支持和怀孕前或怀孕期间控制常见寄生虫感染（特别是疟疾和肠道蠕虫）的干预策略。然而，在需要有针对性的公共卫生努力的资源匮乏地区，进一步研究以确定实现这一目标的障碍和优先方法仍然非常重要。
In the developing world, young women, pregnant women, and their infants and children frequently experience a cycle where undernutrition (macronutrient and micronutrient) and repeated infection, including parasitic infections, lead to adverse consequences that can continue from one generation to the next. Among parasitic infections, malaria and intestinal helminths coexist widely with micronutrient deficiencies and contribute importantly to anemia and this cycle of retarded growth and development. In somewhat more limited or focal geographic settings, other parasitic diseases (e.g., schistosomiasis, filariasis) contribute similarly to this cycle. It is undoubtedly much better to enter a pregnancy free of infection and nutritionally replete than the various alternatives. Existing intervention strategies for micronutrient support and for the control of common parasitic infections before or during pregnancy, particularly malaria and intestinal helminths, should be followed. However, further research to identify barriers and priority approaches to achieving this goal remain very important in resource-poor settings where targeted public health efforts are required.