Case-control study of oral disease indexes in individuals with head and neck cancer after antineoplastic therapy
Case-control study of oral disease indexes in individuals with head and neck cancer after antineoplastic therapy
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头颈癌患者抗肿瘤治疗后口腔疾病指标的病例对照研究
DOI：
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
P. S. Santos
中科院分区：
文献类型：
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作者：
R. A. Quispe;A. L. Cremonesi;Jeanne Kelly Gonçalves;Cassia;P. S. Santos
摘要目的评价头颈部恶性肿瘤患者经正畸治疗后的口腔健康状况，并与无癌史患者进行比较。方法将75例患者分为研究组和对照组，研究组由抗肿瘤治疗后的患者组成（n=30），对照组由无癌症病史的患者组成（n=45），年龄37 ~ 79岁。通过恒牙龋缺充填指数（DMFT）、社区牙周指数、修复体使用和需求评价等指标评价口腔健康状况。所有这些项目都是根据世界卫生组织建议的标准进行评估的。统计分析是描述性的，并使用Pearson χ2检验。结果研究组牙周社区指数明显高于对照组（P<0.0001）。研究组对上部（p<0.001）和下部（p<0.0001）假体的需求更高。此外，研究组中上部假体的使用率较高（p<0.002）。两组恒牙缺失或充填指数（p>0.0506）及低位修复体使用情况（p>0.214）差异无统计学意义。结论牙周病和无牙颌是头颈部恶性肿瘤放疗后最显著的变化，对口腔康复的需求也更大。
ABSTRACT Objective To evaluate the oral health of patients with head and neck cancer after antineoplastic treatment, and to compare them with patients with no history of cancer. Methods A total of 75 patients, divided into Study Group, composed of individuals after antineoplastic treatment (n=30), and Control Group, with individuals with no history of cancer (n=45), aged 37 to 79 years. The oral health status was evaluated through the index of decayed, missing or filled permanent teeth (DMFT), community periodontal index and evaluation of the use and need of prosthesis. All of these items were evaluated according to the criteria recommended by the World Health Organization. The statistical analysis was descriptive and used the Pearson’s χ2 test. Results The community periodontal index was higher in the Study Group when compared to the Control Group (p<0.0001). The need for an upper (p<0.001) and lower (p<0.0001) prostheses was higher in the Study Group. Also, the use of upper prosthesis was higher in the Study Group (p<0.002). The missing or filled permanent teeth index between the two groups (p>0.0506) and the use of lower prosthesis (p>0.214) did not present a relevant statistical difference. Conclusion Periodontal disease and edentulism are the most significant changes in individuals who received antineoplastic therapy for head and neck cancer as well as greater need for oral rehabilitation.
影响因子：
45.3
作者：
Nekhlyudov, Larissa;Lacchetti, Christina;Siu, Lillian L.
通讯作者：
Siu, Lillian L.