The Burden of Cancer in Asian Americans: A Report of National Mortality Trends by Asian Ethnicity.
The Burden of Cancer in Asian Americans: A Report of National Mortality Trends by Asian Ethnicity.
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DOI：
10.1158/1055-9965.epi-16-0167
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发表时间：
2016-10
期刊：
影响因子：
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通讯作者：
Palaniappan LP
中科院分区：
文献类型：
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作者：
Thompson CA;Gomez SL;Hastings KG;Kapphahn K;Yu P;Shariff-Marco S;Bhatt AS;Wakelee HA;Patel MI;Cullen MR;Palaniappan LP
亚裔美国人（AAs）是增长最快的美国人口，当他们的种族来源适当区分时，在社会经济地位，健康行为和健康结果方面表现出很大的异质性。癌症是美国第二大死亡原因，但AA种族人群中癌症死亡率负担的趋势和当前模式尚未记录。我们报告了2003-2011年以下亚裔美国人（AA）种族的年龄调整率，标准化死亡率和癌症相关死亡率的建模趋势：亚洲印度人，中国人，菲律宾人，日本人，韩国人和越南人，非西班牙裔白人（NHW）作为参考人群。对于大多数癌症部位，AAs的癌症死亡率低于NHWs，然而，亚裔美国人种族的死亡率模式是异质的。胃癌和肝癌的死亡率非常高，特别是在中国人、韩国人和越南人中，这两种癌症占癌症死亡的15-25%，但在非卫生工作者中占癌症死亡的不到5%。在AA女性中，肺癌是导致死亡的主要原因，但（与男性和NHW女性不同）在研究期间的发病率并没有下降。种族特异性分析对于了解异质性AA人群中的国家癌症负担至关重要。我们的研究结果强调了在AA中分类报告癌症统计数据的必要性，并保证考虑针对肝癌和胃癌的量身定制的筛查计划。
Asian Americans (AAs) are the fastest growing U.S. population, and when properly distinguished by their ethnic origins, exhibit substantial heterogeneity in socioeconomic status, health behaviors, and health outcomes. Cancer is the second leading cause of death in the US, yet trends and current patterns in the mortality burden of cancer among AA ethnic groups have not been documented. We report age-adjusted rates, standardized mortality ratios, and modeled trends in cancer-related mortality in the following Asian American (AA) ethnicities: Asian Indians, Chinese, Filipinos, Japanese, Koreans, and Vietnamese, from 2003–2011, with non-Hispanic whites (NHW) as the reference population. For most cancer sites, AAs had lower cancer mortality than NHWs, however, mortality patterns were heterogeneous across Asian American ethnicities. Stomach and liver cancer mortality was very high, particularly among Chinese, Koreans, and Vietnamese, for whom these two cancer types combined accounted for 15–25% of cancer deaths, but less than 5% of cancer deaths in NHWs. In AA women, lung cancer was a leading cause of death but (unlike males and NHW females) rates did not decline over the study period. Ethnicity-specific analyses are critical to understanding the national burden of cancer among the heterogeneous AA population. Our findings highlight the need for disaggregated reporting of cancer statistics in AAs, and warrant consideration of tailored screening programs for liver and gastric cancers.