PERIORAL DERMATITIS
PERIORAL DERMATITIS
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DOI：
10.1111/j.1365-2133.1972.tb01590.x
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发表时间：
1972-01-01
影响因子：
10.3
通讯作者：
SNEDDON, I
中科院分区：
文献类型：
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作者：
SNEDDON, I
在过去2年中，在谢菲尔德的鲁珀特哈勒姆皮肤科共观察到73例患者（5例男性和68例女性）患有口周皮炎。除2人外，所有人在患病期间都使用过氟化类固醇。用氢化可的松替代氟化类固醇后，一些患者的病情有所改善，但大多数患者需要土霉素250 mg，每日两次，持续数月才能完全康复。对20名停止治疗6-14个月的患者进行了邮政随访，得到了13个有用的回复。11例患者没有进一步的皮疹，一个轻微的复发，和一个谁曾使用倍他米霜再次，一个严重recursion.It建议，氟化类固醇的应用程序可以改变平庸的皮肤炎症的脸口周皮炎，这种应用程序是禁忌在治疗面部出疹。
Seventy‐three patients, 5 men and 68 women, suffering from perioral dermatitis have been seen in the last 2 years in the Rupert Hallam Department of Dermatology, Sheffield. All but 2 had used fluorinated steroids during the course of their illness. Substitution of hydrocortisone for the fluorinated steroid was followed by improvement in some, but the majority of patients required a course of oxytetracycline 250 mg twice daily for several months to produce complete recovery. A postal follow‐up of 20 patients who had discontinued treatment for 6–14 months gave 13 useful replies. Eleven patients had had no further skin eruption, one a mild recurrence, and one who had used betamethasone cream again, a severe recurrence.It is suggested that fluorinated steroid applications can alter banal skin inflammation of the face into perioral dermatitis and that such applications are contraindicated in the treatment of facial eruptions.