Priapism following a juvenile Russell's viper bite: An unusual case report.
Priapism following a juvenile Russell's viper bite: An unusual case report.
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DOI：
10.1371/journal.pntd.0009242
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发表时间：
2021-03
影响因子：
3.8
通讯作者：
Vaiyapuri S
中科院分区：
文献类型：
--
作者：
Senthilkumaran S;Williams HF;Patel K;Trim SA;Thirumalaikolundusubramanian P;Vaiyapuri S
一名16岁的男性在被幼年拉塞尔蝰蛇（Daboia russelii）咬伤后，阴茎异常勃起（疼痛性勃起）迅速发展，仅在3小时后给予抗蛇毒血清后消退。这种蛇咬伤引起的阴茎异常勃起的潜在机制尚不清楚，但可能是由于毒液毒素引起的一氧化氮（NO）释放和随后的海绵体内皮血管舒张，尽管不能排除其他机制的可能参与。我们坚信，这一不寻常的病例报告可能会导致进一步的科学研究，以提高临床理解的病理生理学envenomation由于罗素的毒蛇咬伤。虽然现在推测还为时过早，但进一步的研究也可能发现开发基于毒液的候选分子来治疗男性和女性性功能障碍的可能性。
Following a bite from a juvenile Russell’s viper (Daboia russelii), a priapism (painful erection) developed rapidly in a 16-year-old male and only subsided after administration of antivenom 3 hours later. Potential mechanisms for this snakebite-induced priapism are unclear but likely due to venom toxins causing nitric oxide (NO) release and subsequent vasodilation of endothelium in the corpus cavernosum, although the possible involvement of other mechanisms cannot be ruled out. We strongly believe that this unusual case report may lead to further scientific research in order to improve the clinical understanding of the pathophysiology of envenomation due to Russell’s viper bites. Although it is too early to speculate, further research may also discover the possibilities of developing venom-based candidate molecules to treat sexual dysfunction in males and females.
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影响因子：
6.6
作者：
Silva, Carolina Nunes;Nunes, Kenia Pedrosa;de Lima, Maria Elena
通讯作者：
de Lima, Maria Elena
影响因子：
15.8
作者：
Kasturiratne A;Wickremasinghe AR;de Silva N;Gunawardena NK;Pathmeswaran A;Premaratna R;Savioli L;Lalloo DG;de Silva HJ
通讯作者：
de Silva HJ
DOI：
10.3909/riu0768
发表时间：
2017-01-01
期刊：
Reviews in urology
影响因子：
--
作者：
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通讯作者：
Mattioli, Girolamo
影响因子：
7.3
作者：
Hallen, K.;Wiklund, N. P.;Gustafsson, L. E.
通讯作者：
Gustafsson, L. E.
影响因子：
1.4
作者：
Goel, Sheila Choudhury;Yabrodi, Mouhammad;Fortenberry, James
通讯作者：
Fortenberry, James