Trend in incidence of gastric adenocarcinoma by tumor location from 1969-2004: a study in one referral center in Iran.
Trend in incidence of gastric adenocarcinoma by tumor location from 1969-2004: a study in one referral center in Iran.
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DOI：
10.1186/1746-1596-1-5
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发表时间：
2006-05-11
影响因子：
2.6
通讯作者：
中科院分区：
文献类型：
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作者：
近年来，一些研究表明，相对于远端胃癌的减少，上部胃癌的发病率增加。本研究的目的是描述伊朗各地区胃癌的趋势，伊朗是胃癌高发国家之一。对1969年至2004年德黑兰癌症研究所登记的所有胃切除术病例进行临床病理学重新评价。胃在解剖学上分为上、中、下三分之一。分别从年龄和性别两个方面对5年内不同地区的胃癌患病率及其随时间的变化进行了评价。36年来，胃的上三分之一和中三分之一的癌症发病率有所增加，而下三分之一的癌症发病率有所下降。这些变化在50岁以下和50岁以上的性别和年龄组中都有发现，在年轻人中更为明显。结果与其他国家的大多数先前报告相同。这可能表明不同的风险因素以及与它们的对抗。但是，鉴于本研究中的病例数量较少，建议进行基于人群的研究进行确认。
In recent years several studies have shown increasing rate of upper gastric cancers regarding to decrease in distal gastric cancers. The aim of this study was to describe the trend of gastric cancers by location in Iran, which is one of the countries with high prevalence of gastric cancers. All registered cases of gasterectomy in Tehran Cancer Institute from 1969 through 2004 were re-evaluated clinicopathologically. The stomach was anatomically divided into the upper, middle, and lower third. The prevalence of gastric cancers in 5 year periods estimated by location and the changes trough the time was evaluated independently and in aspect of age and sex. Over 36 years, the prevalence of cancers in the upper and middle third of the stomach have increased and that of the lower third has decreased. These changes were seen in both sexes and age groups under and over 50 and it was more significant in younger. The results are the same as most previous reports in other countries. This can indicate different risk factors as well as confrontation with them. However in regard to few numbers of cases in this study, a population-based study is recommended for confirmation.