Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species
Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species
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DOI：
10.1128/aem.01537-10
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发表时间：
2010-12-01
影响因子：
4.4
通讯作者：
Gallivan, Justin P.
中科院分区：
文献类型：
--
作者：
Topp, Shana;Reynoso, Colleen M. K.;Gallivan, Justin P.
我们开发了一系列配体诱导型核糖开关，其控制革兰氏阴性和革兰氏阳性细菌的不同物种中的基因表达，包括具有很少或没有先前报道的诱导型表达系统的人类病原体。我们预计，这些核糖开关将是有用的工具，在广泛的细菌遗传研究。
We developed a series of ligand-inducible riboswitches that control gene expression in diverse species of Gram-negative and Gram-positive bacteria, including human pathogens that have few or no previously reported inducible expression systems. We anticipate that these riboswitches will be useful tools for genetic studies in a wide range of bacteria.