HDR imaging evaluation of a NT-proBNP test with a mobile phone
HDR imaging evaluation of a NT-proBNP test with a mobile phone
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DOI：
10.1016/j.bios.2010.09.015
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发表时间：
2011-01-15
影响因子：
12.6
通讯作者：
Filippini, D.
中科院分区：
文献类型：
--
作者：
Preechaburana, P.;Macken, S.;Filippini, D.
NT-proBNP水平的测定是监测诊断为心力衰竭的患者的关键，并且是通常在医疗保健中心进行的常规测量，这将受益于分散的替代品。在这里，我们研究了使用标准移动的电话对成熟的NT-proBNP检测的定量评价（Nokia 6720）作为测量平台，而不是专用仪器。为此应用开发的Java ME软件在规定的时间间隔内控制proBNP测试的照明和成像，其使得能够合成被处理为高动态范围（HDR）的多曝光集对比度增强的图像。结果表明，HDR处理显着提高了该技术的灵敏度和分辨率，实现了诊断范围内的性能。这些结果表明，利用无处不在的设备来分散评估常规测试，并确定关键的处理替代方案，使这些系统的性能在诊断范围内。(C)2010 Elsevier B. V.保留所有权利。
The determination of NT-proBNP levels is key for the monitoring of patients with diagnosed heart failure and it is a routine measurement typically performed at health care centers, which would benefit from decentralized alternatives.Here we investigate the quantitative evaluation of a well-established NT-proBNP test using a standard mobile phone (Nokia 6720) as measuring platform rather than a dedicated instrument.A Java ME software developed for this application controls the illumination and imaging of the proBNP test under defined time intervals, which enables the composition of multi-exposure sets that are processed as high dynamic range (HDR) images for contrast enhancement.The results show that HDR processing significantly increases the sensitivity and resolution of the technique achieving a performance within the diagnostics range.These results demonstrate the feasibility to exploit a ubiquitous device to decentralize the evaluation of a routine test and identify key processing alternatives to bring the performance of such systems within the diagnostics range. (C) 2010 Elsevier B.V. All rights reserved.