T1 mapping of the entire lung parenchyma: Influence of the respiratory phase in healthy individuals

T1 mapping of the entire lung parenchyma: Influence of the respiratory phase in healthy individuals
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DOI:
10.1002/jmri.20319
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发表时间:
2005-06-01
影响因子:
4.4
通讯作者:
Bankier, AA
Bankier, AA
中科院分区:
医学2区
文献类型:
--
作者:
Stadler, A;Jakob, PM;Bankier, AA

文献摘要

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目的:为了确定呼吸阶段的T I值的影响,整个lung.Materials和方法:我们计算T1弛豫时间的一个像素的像素分析一系列的快照FLASH断层扫描后获得一个单一的反转脉冲。两套冠状T1地图采集,一个在完全暂停吸气和暂停expiration.Results:在整个肺的平均T1值的平均值在吸气为1199 +/- 117毫秒,平均T1值在呼气为1333 +/- 167毫秒。该差异具有统计学显著性,P = 0.005。在灵感的平均系数。变异为182 ± 56毫秒,呼气时为153 ± 41毫秒。结论:T1测量整个肺是可行的。我们的研究结果强调,需要密切监测的吸气状态在MR检查的胸部,特别是当T1测量肺进行。
Purpose: To determine the effect of respiratory phase on the T I values of the entire lung.Materials and Methods: We calculated T1 relaxation time on a pixel-by-pixel analysis of a series of Snapshot FLASH tomograms acquired after a single inversion pulse. Two sets of coronal T1 maps were acquired, one in full suspended inspiration and one in suspended expiration.Results: The average of the mean T1 values over the entire lung in inspiration was 1199 +/- 117 msec, the average of the mean T1 values in expiration was 1333 +/- 167 msec. This difference was statistically significant, at P = 0.005. In inspiration the average coefficient. of variation was 182 56 msec, in expiration it was 153 +/- 41 msec. This difference was not statistically significant.Conclusion: T1 measurements of the entire lung are feasible. Our findings underline the need for a close monitoring of the inspirational status during MR examinations of the thorax, notably when T1 measurements of the lung are performed.