Trends in Disease Severity and Health Care Utilization During the Early Omicron Variant Period Compared with Previous SARS-CoV-2 High Transmission Periods - United States, December 2020-January 2022
Trends in Disease Severity and Health Care Utilization During the Early Omicron Variant Period Compared with Previous SARS-CoV-2 High Transmission Periods - United States, December 2020-January 2022
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DOI：
10.1101/2021.12.30.21268560v2
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发表时间：
2022-01-28
影响因子：
33.9
通讯作者：
Ritchey, Matthew D.
中科院分区：
文献类型：
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作者：
Iuliano, A. Danielle;Brunkard, Joan M.;Ritchey, Matthew D.
关于这个话题我们已经知道了什么？到2021年12月下旬，SARS-CoV-2 B.1.1.529 （Omicron）变体在美国占主导地位，导致COVID-19病例以及相关的急诊科就诊和住院人数激增。这份报告增加了什么内容？尽管欧米克隆在大流行期间报告的COVID-19病例和住院人数最多，但疾病严重程度指标，包括住院时间、ICU住院和死亡，都低于之前的大流行高峰期。这对公共卫生实践有什么影响？虽然Omicron变体的疾病严重程度似乎较低，但大量住院治疗可能给当地卫生保健系统带来压力，平均每日死亡人数仍然很大。这强调了国家应急准备的重要性，特别是医院快速应变能力和为地方卫生保健系统配备充足人员的能力。此外，及时接种疫苗并遵循其他建议的预防策略对于预防COVID-19感染、严重疾病或死亡至关重要。
What is already known about this topic?The SARS-CoV-2 B.1.1.529 (Omicron) variant became predominant in the United States by late December 2021, leading to a surge in COVID-19 cases and associated ED visits and hospitalizations.What is added by this report?Despite Omicron seeing the highest reported numbers of COVID-19 cases and hospitalizations during the pandemic, disease severity indicators, including length of stay, ICU admission, and death, were lower than during previous pandemic peaks.What are the implications for public health practice?Although disease severity appears lower with the Omicron variant, the high volume of hospitalizations can strain local health care systems and the average daily number of deaths remains substantial. This underscores the importance of national emergency preparedness, specifically, hospital surge capacity and the ability to adequately staff local health care systems. In addition, being up to date on vaccinations and following other recommended prevention strategies are critical to preventing infections, severe illness, or death from COVID-19.