NATURALLY-OCCURRING AUXIN TRANSPORT REGULATORS
NATURALLY-OCCURRING AUXIN TRANSPORT REGULATORS
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DOI：
10.1126/science.241.4863.346
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发表时间：
1988-07-15
期刊：
影响因子：
56.9
通讯作者：
RUBERY, PH
中科院分区：
文献类型：
--
作者：
JACOBS, M;RUBERY, PH
植物生长素极性转运是植物生长素关系的核心，它可以被一组合成化合物所抑制，这些化合物显然是通过与一种被称为萘酞酸（NPA）受体的质膜蛋白结合而起作用的。目前还没有发现能影响植物生长素极性转运的NPA受体的内源性配体。现在研究表明，一组黄酮类化合物，包括槲皮素、芹菜素和山奈酚，可以特异性地与[3H]NPA结合受体竞争，并以与合成运输抑制剂相似的方式干扰植物组织和运输系统中的生长素运输。由于活性黄酮类化合物广泛分布于植物界，并在接近内源水平的微摩尔浓度下发挥作用，它们可能是植物中天然的生长素运输调节剂。
The process of polar auxin transport, central to a plant''s auxin relations, can be inhibited by a group of synthetic compounds that apparently act by binding to a plasma membrane protein known as the naphthylphthalamic acid (NPA) receptor. No endogenous ligand to the NPA receptor, capable of affecting polar auxin transport in plants, has yet been found. It is now shown that a group of flavonoids.sbd.including quercetin, apigenin, and kaempferol.sbd.can specifically compete with [3H]NPA for binding to its receptor and can perturb auxin transport in a variety of plant tissues and transport systems in a manner closely paralleling the action of synthetic transport inhibitors. Because the active flavonoids are widely distributed in the plant kingdom and exert their effects at micromolar concentrations approximating likely endogenous levels, they may act as natural auxin transport regulators in plants.