Etiology of borderline personality disorder - Disentangling the contributions of intercorrelated antecedents
Etiology of borderline personality disorder - Disentangling the contributions of intercorrelated antecedents
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DOI：
10.1097/01.nmd.0000149215.88020.7c
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发表时间：
2005-01-01
影响因子：
1.9
通讯作者：
Westen, D
中科院分区：
文献类型：
--
作者：
Bradley, R;Jenei, J;Westen, D
大量的研究指出了与边缘型人格障碍（BPD）病因相关的几个变量，特别是童年时期的身体虐待和性虐待，童年家庭环境，以及内化和外化障碍的家庭聚集。然而，这些变量往往是相关的，很少有研究同时检查它们。在全国范围内随机抽取的心理学家和精神病学家的样本描述了524名患有人格障碍的成年患者。在多元回归分析中，家庭环境、父母精神病理和虐待史都能独立预测BPD症状。性虐待在预测BPD症状方面的作用超过家庭环境，尽管家庭环境因素如不稳定性部分介导了这种影响。这些结果与最近使用不同样本和方法的研究结果一致。
A substantial body of research points to several variables relevant to the etiology of borderline personality disorder (BPD), notably childhood physical and sexual abuse, childhood family environment, and familial aggregation of both internalizing and externalizing disorders. However, these variables tend to be correlated, and few studies have examined them simultaneously. A national sample of randomly selected psychologists and psychiatrists described 524 adult patients with personality disorders. Family environment, parental psychopathology, and history of abuse all independently predicted BPD symptoms in multiple regression analyses. Sexual abuse contributed to the prediction of BPD symptoms over and above family environment, although family environmental factors such as instability partially mediated the effect. The results converge with recent studies using very different samples and methodologies.