Risk of spontaneous abortion in Italy, 1978-1995, and the effect of maternal age, gravidity, marital status, and education
Risk of spontaneous abortion in Italy, 1978-1995, and the effect of maternal age, gravidity, marital status, and education
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DOI：
10.1093/oxfordjournals.aje.a010128
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发表时间：
2000-01-01
影响因子：
5
通讯作者：
Spinelli, A
中科院分区：
文献类型：
--
作者：
Osborn, JF;Cattaruzza, MS;Spinelli, A
本文描述了1974年至1995年意大利自然流产风险的趋势。1978年人工流产合法化的法律通过后，风险急剧下降，这意味着可能有许多1978年之前进行的人工流产被登记为自然流产。 1991 年的数据是从意大利国家出生和堕胎登记中提取的，并进行了分析，以调查母亲年龄、怀孕情况、婚姻状况和教育程度对自然流产风险的影响。与 20 岁以下的女性相比，35-39 岁的女性（优势比 = 1.45）和 40 岁以上的女性（优势比 = 3.10）的风险更高。对于之前怀孕两次或两次以上的女性来说，优势比几乎为 2。未婚女性的风险增加（比值比 = 1.33），但没有观察到教育的重要影响。母亲年龄和怀孕次数之间存在重要的相互作用。对于高妊娠的年轻女性来说，自然流产的风险极高。据推测，这可能是由于怀孕间隔短的影响。
This paper describes the trend in the risk of spontaneous abortion in Italy from 1974 to 1995. There was a dramatic decline in the risk after the law that legalized induced abortion was passed in 1978, which implies that probably many induced abortions performed before 1978 were registered as spontaneous abortions. Data for 1991 have been extracted from the Italian national registers of births and abortions and analyzed to investigate the effects of maternal age, gravidity, marital status, and education on the risk of spontaneous abortion. in comparison with women under age 20 years, the risk is found to be increased for women aged 35-39 (odds ratio = 1.45) end women over age 40 (odds ratio = 3.10). The odds ratio is almost 2 for women who have been pregnant two or more times previously. Unmarried women have an increased risk (odds ratio = 1.33), but no important effect of education was observed. There is an important interaction between maternal age and gravidity. The risk of spontaneous abortion is excessively high for young women with high gravidity. It is hypothesized that this could be due to the effect of short intervals between pregnancies.