A method for calibrating three-dimensional positron emission tomography without scatter correction
A method for calibrating three-dimensional positron emission tomography without scatter correction
复制标题
一种无需散射校正的三维正电子发射断层扫描校准方法
DOI：
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
T. Jones
中科院分区：
文献类型：
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作者：
D. Bailey;T. Jones
使用均匀圆柱体的三维正电子发射断层扫描 (3D PET) 校准和等分试样的交叉校准需要对散射和衰减进行校正。因此，校准的准确性取决于散射校正方法以及散射校正对于身体的不同区域的适用性。已经开发出一种方法，该方法提供不需要散射或衰减校正的校准，使其普遍适用并且独立于散射校正。先前已经描述了用于测量断层扫描设备的绝对灵敏度的方法。此方法已扩展为“在空气中”以 kBq/像素为单位对 PET 相机进行校准。重建图像乘以该因子，在衰减和散射校正后给出准确的活性浓度。该方法已与全 3D 滤波反投影（重投影）算法以及对 ECAT 953B 数据的迭代卷积减法散射校正一起使用。使用这种方法，3D PET 图像已被校准，精度在 ±5% 之内，但这在很大程度上取决于散射校正的精度。这里描述的方法很实用，提供了一种校准 3D PET 系统的方法，无需对校准数据的散射或衰减进行校正。
Calibration for three-dimensional positron emission tomography (3D PET) using a uniform cylinder and cross-calibration with aliquots requires correction for scatter and attenuation. Thus the accuracy of thecalibration is dependent on the scatter correction method, and on the applicability of the scatter correction for different regions of the body. A method has been developed which provides a calibration which does not require correction for scatter or attenuation, making it generally applicable and independent of the scatter correction. The method has been previously described for measurement of the absolute sensitivity of tomography devices. This approach has been extended to give a calibration of the PET camera “in air” in units of kBq/pixel. The reconstructed images are multiplied by this factor to, give accurate activity concentrations, after attenuation and scatter correction. The method has been used with a fully 3D filtered back-projection (reprojection) algorithm and iterative convolution-subtraction scatter correction on data from an ECAT 953B. Using this method 3D PET images have been calibrated te, within ±5% accuracy, but this is highly dependent on the accuracy of the scatter correction. The method described here is practical and provides a means of calibrating a 3D PET system without the need for correction for scatter or attenuation of the calibration data.
使用带有可伸缩隔膜的扫描仪对三维 PET 中的散射事件进行校正和表征。
DOI：
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发表时间：
1993
期刊：
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
影响因子：
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作者：
Cherry,SR;Meikle,SR;Hoffman,EJ
通讯作者：
Hoffman,EJ