A prospective study of the effects of age of initiation of alcohol and drug use on young adult substance dependence
A prospective study of the effects of age of initiation of alcohol and drug use on young adult substance dependence
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DOI：
10.15288/jsad.2007.68.256
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发表时间：
2007-03-01
影响因子：
3.4
通讯作者：
Chassin, Laurie
中科院分区：
文献类型：
--
作者：
King, Kevin M.;Chassin, Laurie
目的：以前的横断面研究不同意青少年开始饮酒的年龄是否是后来酒精依赖的唯一预测因素，或者它是否仅仅是产生酒精依赖的因素的相关性。当前的研究在纵向样本中测试了这个问题，并通过测试开始饮酒和吸毒的年龄是否可以预测酒精和药物依赖来扩展文献。方法：一项正在进行的研究中的酗酒者和匹配的对照组（n = 395）的儿童的数据收集在三个年度的采访在青春期和两个5年的随访在年轻的成年。结果如下：当青少年没有参与早期药物使用或考虑相关风险因素时，在13岁或之前首次饮酒与酒精和药物依赖的几率无关。另一方面，即使在控制了共同的风险因素的情况下，早期使用药物也会增加年轻人的药物依赖几率。结论：目前的研究支持了这样一种观点，即青少年早期开始饮酒是后来依赖的风险标志，而不是因果关系。此外，它还提供了早期吸毒对药物依赖性影响的证据。理论和干预的影响进行了讨论。
Objective: Previous cross-sectional research has disagreed about whether an adolescent's age of onset of alcohol use is a unique predictor of later alcohol dependence or whether it is merely a correlate of those factors that produce alcohol dependence. Tile current study tests this question in a longitudinal sample, and extends the literature by testing whether age of onset of alcohol and drug use predicts alcohol and drug dependence. Method: Data from an ongoing study of children of alcoholics and matched controls (n = 395) were collected during three annual interviews during adolescence and two 5-year follow-ups in young adulthood. Results: Taking a first drink of alcohol at or before age 13 was unrelated to the odds of alcohol and drug dependence when the adolescent did not also participate in early drug use or when correlated risk factors were taken into account. On the other hand, early drug use elevated the odds of drug dependence by young adulthood, even while controlling for shared risk factors. Conclusions: The current study provides support for the notion that early-adolescent onset of alcohol use is a marker of risk for later dependence rather than a causal influence. Moreover, it provides evidence for the impact of early drug use on drug-substance dependence. Implications for theory and intervention are discussed.