Chromium picolinate.
Chromium picolinate.
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吡啶甲酸铬。
DOI：
10.4135/9781412963862.n94
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
S. Reading
中科院分区：
文献类型：
--
作者：
S. Reading
吡啶甲酸铬是一种膳食补充剂，在美国人中越来越受欢迎，尤其是那些寻求减肥计划的人。尽管吡啶甲酸铬的作用机制尚未得到彻底研究，但研究表明吡啶甲酸铬的生化、生理和行为作用可能是吡啶甲酸对中枢神经系统影响的结果。吡啶甲酸类似物已被证明可引起大脑中血清素、多巴胺和去甲肾上腺素代谢的深刻改变。因此，应谨慎使用吡啶甲酸铬补充剂，尤其是容易出现行为障碍的个体。
Chromium picolinate is a dietary supplement gaining in popularity among Americans, especially those seeking a weight-reduction program. Although the mechanism(s) responsible for the purported actions of chromium picolinate have not been thoroughly investigated, studies suggest that the biochemical, physiological, and behavioral actions of chromium picolinate may be a consequence of the effects of picolinic acid on the central nervous system. Analogues of picolinic acid have been shown to induce profound alterations in the metabolism of serotonin, dopamine, and norepnephrine in brain. Thus, caution should be used with chromium picolinate supplements especially by individuals prone to behavioral disorders.