Individualized anemia management using a radial basis function method

Individualized anemia management using a radial basis function method
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使用径向基函数方法进行个体化贫血管理

DOI:
10.1109/glbc.2015.7158301
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发表时间:
2015
期刊:
2015 IEEE Great Lakes Biomedical Conference (GLBC)
影响因子:
--
通讯作者:
T. Inanc
T. Inanc
中科院分区:
--
文献类型:
--
作者:
Hossein Mirinejad;T. Inanc

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提出了一种基于径向基函数(RBF)的肾性贫血给药优化控制方法。贫血症的管理制定为一个约束最优控制问题,并解决了径向基函数方法。径向基函数方法是一种利用径向基函数参数化和正交离散化将最优控制问题转化为非线性规划问题的数值方法。然后,基于RBF方法的滚动时域控制方法被开发用于个体化贫血管理。仿真结果进行了比较,从临床协议,以验证所提出的方法的效率。
This paper presents a radial basis function (RBF) solution to the optimal control of drug administration in renal anemia treatment. Anemia management is formulated as a constrained optimal control problem and solved by an RBF method. RBF method is a numerical approach using RBF parameterization and orthogonal discretization to transcribe the optimal control problem into a nonlinear programming (NLP) problem. Then, a receding horizon control approach based on the RBF method is developed for individualized anemia management. The simulation results are compared with those obtained from a clinical protocol to verify the efficiency of the proposed method.
DOI: 10.1053/j.ajkd.2007.10.003
发表时间: 2008-01-01
影响因子: 13.2
作者:
Gaweda, Adam E.;Jacobs, AlfredA.;Brier, Michael E.
通讯作者: Brier, Michael E.