The effects of 10 weeks of resistance training combined with β-alanine supplementation on whole body strength, force production, muscular endurance and body composition
The effects of 10 weeks of resistance training combined with β-alanine supplementation on whole body strength, force production, muscular endurance and body composition
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DOI：
10.1007/s00726-007-0008-3
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发表时间：
2008-05-01
期刊：
影响因子：
3.5
通讯作者：
Wise, John A.
中科院分区：
文献类型：
--
作者：
Kendrick, Iain P.;Harris, Roger C.;Wise, John A.
肌肽（卡恩）以高浓度存在于骨骼肌中，是生理范围内H+的有效物理化学缓冲剂。最近的研究表明，β-丙氨酸（β-ala）的g.day（-1）可以显著增加骨骼肌卡恩浓度（M-[卡恩]），同时缓冲能力的结果变化已经被运动表现的无氧和有氧测量的显著改善所抵消。肌肉肌肽的增加也与阻力训练期间所做的工作增加有关。先前的研究表明，力量训练也可能增加M-[卡恩]，尽管这是有争议的其他研究。本研究的目的是评估10周抗阻训练对M-[卡恩]的影响，其次，研究通过β-丙氨酸补充剂引起的M-[卡恩]增加是否对训练反应有积极影响。26名越南体育科学专业的学生完成了这项研究。受试者完成了为期10周的阻力训练计划，同时消耗g.day-1）的β-丙氨酸（β-ALG）或匹配剂量的安慰剂（PLG）。受试者在训练前后进行全身力量、等速肌力、肌肉耐力和身体成分的评估。补充β-丙氨酸的受试者使M-[卡恩]增加12.81 +/- 7.97（-1）干肌肉，而PLG受试者没有变化。mmol.kg补充β-丙氨酸对任何测量的运动参数，体重或%体脂没有显著影响。总之，10周的单独阻力训练并没有改变M-[卡恩]。
Carnosine (Carn) occurs in high concentrations in skeletal muscle is a potent physico-chemical buffer of H+ over the physiological range. Recent research has demonstrated that 6.4 g.day(-1) of beta-alanine (beta-ala) can significantly increase skeletal muscle Carn concentrations (M-[Carn]) whilst the resultant change in buffering capacity has been shown to be paralleled by significant improvements in anaerobic and aerobic measures of exercise performance. Muscle carnosine increase has also been linked to increased work done during resistance training. Prior research has suggested that strength training may also increase M-[Carn] although this is disputed by other studies. The aim of this investigation is to assess the effect of 10 weeks resistance training on M-[Carn], and, secondly, to investigate if increased M-[Carn] brought about through beta-ala supplementation had a positive effect on training responses. Twenty-six Vietnamese sports science students completed the study. The subjects completed a 10-week resistance-training program whilst consuming 6.4 g.day(-1) of beta-ala (beta-ALG) or a matched dose of a placebo (PLG). Subjects were assessed prior to and after training for whole body strength, isokinetic force production, muscular endurance, body composition. beta-Alanine supplemented subjects increased M-[Carn] by 12.81 +/- 7.97 mmol.kg(-1) dry muscle whilst there was no change in PLG subjects. There was no significant effect of beta-ala supplementation on any of the exercise parameters measured, mass or % body fat. In conclusion, 10 weeks of resistance training alone did not change M-[Carn].