Hormonal control of turnover of tyrosine and tyrosine phosphate during tanning of the adult cuticle in the fly, Sarcophaga bullata.
Hormonal control of turnover of tyrosine and tyrosine phosphate during tanning of the adult cuticle in the fly, Sarcophaga bullata.
复制标题
果蝇（Sarcophaga bullata）成虫角质层晒黑过程中酪氨酸和酪氨酸磷酸转换的激素控制。
DOI：
10.1016/0022-1910(69)90146-2
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发表时间：
1969
影响因子：
2.2
通讯作者：
G. Fraenkel
中科院分区：
文献类型：
--
作者：
M. Seligman;S. Friedman;G. Fraenkel
14C-酪氨酸在果蝇羽化后注入体内的唯一可溶代谢产物是酪氨酸-O-磷酸。在有和没有成人晒黑激素的情况下，对其周转的动力学研究表明，它可能不是制革过程中的中间产物。它的受体可能是代谢可及的酪氨酸的储存库。然而，由于酪氨酸的比活性在成虫羽化后的前5小时内下降，并且没有足够的酪氨酸磷酸来解释观察到的稀释率，因此认为蛋白质或多肽前体在这个时候被降解。14C赖氨酸的平行稀释率支持了这种可能性。
The only soluble metabolite of14C-tyrosine injected into flies as they emerge from their puparia is tyrosine-O-phosphate. A kinetic study of its turnover in the presence and absence of the adult tanning hormone, bursicon, indicates that it is probably not an intermediate in the tanning process. Its rôle may be that of a store of metabolically accessible tyrosine. However, since the specific activity of tyrosine falls during the first 5 hr of adult life after emergence and there is insufficient tyrosine phosphate to account for the observed dilution rates, it is suggested that a proteinaceous or peptide precursor is degraded at this time. The parallel dilution rate of14C lysine lends support to this possiblity.