MEMBRANE ADENOSINE TRIPHOSPHATASE AND CATION TTANSPORT
MEMBRANE ADENOSINE TRIPHOSPHATASE AND CATION TTANSPORT
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DOI：
10.1093/oxfordjournals.bmb.a070620
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发表时间：
1968-01-01
影响因子：
6.7
通讯作者：
GLYNN, IM
中科院分区：
文献类型：
--
作者：
GLYNN, IM
现在人们普遍认为，大多数动物细胞中K+离子的高浓度和Na+离子的低浓度依赖于膜上的泵的活性，泵利用三磷酸腺苷(ATP)水解产生的能量来积累K+离子和排出Na+离子。这篇综述的目的是总结证明这一观点的证据，并简要介绍最近的工作，这些工作提供了关于泵机制性质的一些信息。关于到1965年为止的时期的更详细的评论，见Skou(1965)和Glynn(1966)；Heinz(1967)的评论提供了最近参考文献的有用来源。
It is now widely believed that the high concentration of K+ ions and the low concentration of Na+ ions found in most animal cells depend on the activity of a pump, in the membrane, which uses energy from the hydrolysis of adenosine triphosphate (ATP) to accumulate K+ ions and expel Na+ ions. The aim of this review is to summarize the evidence that justifies this belief, and to give a brief account of recent work that has provided a little information about the nature of the pump mechanism. For more detailed reviews covering the period up to 1965 see Skou (1965) and Glynn (1966); a review by Heinz (1967) provides a useful source of recent references.