Re‐entrainment of circadian rhythm of plasma melatonin on an 8‐h eastward flight

Re‐entrainment of circadian rhythm of plasma melatonin on an 8‐h eastward flight
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向东飞行 8 小时时血浆褪黑素昼夜节律的重新夹带

DOI:
10.1046/j.1440-1819.1999.00537.x
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发表时间:
1999
影响因子:
11.9
通讯作者:
N. Matsunaga
N. Matsunaga
中科院分区:
医学2区
文献类型:
--
作者:
Toshiharu Takahashi;M. Sasaki;H. Itoh;H. Sano;W. Yamadera;M. Ozone;Keita Obuchi;Hiroshi Nishimura;N. Matsunaga

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为了估计再夹带的过程,我们测量了向东飞行的褪黑激素节律。基线研究后,在第1天和第5天对6例男性受试者进行24小时血样采集。在白天,受试者每天暴露于户外自然授时因子,采血日除外。在强光条件下用照度计分析。6例受试者中有4例显示顺向再夹带,另1例受试者显示逆向再夹带,另1例受试者保持血浆褪黑激素的基线模式。顺向再夹带的再夹带率约为每天55分钟。测量血浆褪黑激素的昼夜节律已经澄清了个体间的再夹带差异。
To estimate the process of re‐entrainment we measured the melatonin rhythm on an eastward flight. After the baseline study, 24‐hour blood sampling of six male subjects was done on the first and fifth days. During the daytime the subjects were exposed to natural zeitgeber outdoors every day except the blood sampling day. They were analyzed with an illuminometer when under the bright light condition. Four of the six subjects showed orthodromic re‐entrainment, another subject showed antidromic re‐entrainment, and the other subject kept the baseline pattern of plasma melatonin. The rate of re‐entrainment in orthodromic re‐entrainment was about 55 min per day. Measuring the circadian rhythm of plasma melatonin has clarified the inter‐individual re‐entrainment difference.