Risk factors for foot and mouth disease seroprevalence in indigenous cattle in Southern Ethiopia: the effect of production system
Risk factors for foot and mouth disease seroprevalence in indigenous cattle in Southern Ethiopia: the effect of production system
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DOI：
10.1007/s11250-008-9276-5
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发表时间：
2009-08-01
影响因子：
1.7
通讯作者：
Rufael, T.
中科院分区：
文献类型：
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作者：
Megersa, B.;Beyene, B.;Rufael, T.
2007年10月至2008年3月在埃塞俄比亚南部进行了一项血清学调查，以调查口蹄疫发生的危险因素。检测口蹄疫病毒非结构蛋白抗体(采用3abc-EL ISA)作为暴露于该病毒的指标。动物和畜群水平口蹄疫血清阳性率分别为9.5%(95%CI=7.7~11.3，n=1020)和48.1%(95%CI=36.8~59.4%，n=79)。群内血清阳性率为6.7%~46.7%，阳性群中动物为阳性的风险为18.6%(95%CI=14.6~22.5%)。最重要的畜群水平危险因素是牧区系统(OR=16.3，95%CI=2.0~133.7)，与高海拔地区相比，低海拔、久坐不动(OR=7.5，95%CI 1.4~40.7)，与单一物种或单独饲养小反刍动物相比，养牛(OR=5.1，95%CI 1.0~2 5.2)。Omo南部地区的血清阳性率显著高于Sidama和Gamo Gofa地区(P<；0.05)。成年(4岁)和成熟动物(3-4岁)的血清阳性几率分别是年轻年龄组(3岁)的2.8倍和2.3倍。多因素Logistic回归和负二项回归分析均显示生产系统是口蹄疫血清阳性的主要危险因素。因此，在畜牧系统中，动物是生活中不可或缺的一部分，口蹄疫的发病率较高，这对生计和经济都有重大影响，这意味着需要制定控制措施。
A serological survey to investigate risk factors for Foot and Mouth Disease (FMD) occurrence was conducted between October 2007 and March 2008 in Southern Ethiopia. Antibodies against non-structural protein of FMD virus (using 3abc ELISA) were measured as indicator of exposure to the virus. The seroprevalence of FMD was 9.5% (95%CI = 7.7 - 11.3, n = 1020) and 48.1% (95% CI = 36.8 - 59.4%, n = 79), respectively at animal and herd levels. Within herd seropositivity was ranged from 6.7 to 46.7% with 18.6% (95%CI = 14.6 - 22.5%) risk of being seropositive for an animal in positive herds. The most important herd level risk factors identified were pastoral system (OR = 16.3, 95% CI = 2.0 -133.7) compared to sedentary, low altitude (OR = 7.5, 95% CI 1.4 -40.7) compared to high altitude, keeping cattle with small ruminants (OR = 5.1, 95% CI 1.0 -25.2) when compared to one species or alone. Seroprevalence was significantly higher (P < 0.05) in South Omo than Sidama and Gamo Gofa areas. The odds of seropositivity were 2.8 and 2.3 times higher in the adult (> 4 years) and maturing animals (3-4 years) compared to young age category (< 3 years). Both multivariable logistic and negative binomial regressions depicted that production system was the major risk factor for FMD seropositivity. Consequently, higher prevalence of FMD in pastoral system where animals are an integral part of life has substantial livelihood and economic implications, which signifies the need for devising control measures.