The basal ganglia in reward and decision making: computational models and empirical studies
The basal ganglia in reward and decision making: computational models and empirical studies
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DOI：
10.1016/b978-0-12-374620-7.00019-4
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发表时间：
2009-01-01
期刊：
影响因子：
--
通讯作者：
Frank, Michael J.
中科院分区：
文献类型：
--
作者：
Doll, Bradley B.;Frank, Michael J.
The basal ganglia (BG) are implicated in a wide variety of motor and cognitive behaviors, making it difficult to extract a unifying function of these brain structures. We review a series of neurocomputational models that focus on the action selection and reinforcement learning functions of the BG, and their modulation by dopamine, as constrained by a broad range of data. We begin with the "basic" model, which forms the core mechanism for later appended models including the roles of norepinephrine, cognitive and affective components of prefrontal cortex, and the interaction between verbal instructions and reinforcement learning. We further review experiments designed to test model predictions as a function of disease, medications, genetics, and behavioral manipulations. Abstract mathematical models that have been used in conjunction with these accounts are also discussed.
