Pre-cancer: From diagnosis to intervention opportunities.

Pre-cancer: From diagnosis to intervention opportunities.
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癌症前期:从诊断到干预机会。

DOI:
10.1016/j.ccell.2023.03.012
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发表时间:
2023
期刊:
影响因子:
50.3
通讯作者:
Hwang ES
Hwang ES
中科院分区:
医学1区
文献类型:
--
作者:
Hwang ES

文献摘要

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致癌的多步骤过程意味着存在癌前但改变的状态,涉及潜在的致癌细胞及其周围的微环境。专家们讨论了一些已经确定了明确的癌前阶段的肿瘤类型,并提到了用于诊断和干预策略的关键生物学改变。
The multi-step process of carcinogenesis implies the existence of pre-malignant yet altered states that involve both the potentially carcinogenic cell as well as its surrounding microenvironment. Experts discuss some tumor types for which clear pre-cancerous stages have been identified and mention key biological alterations used for diagnosis and intervention strategies.