The use of intermittent and continuous recordings of jugular venous bulb oxygen saturation in the unconscious patient.
The use of intermittent and continuous recordings of jugular venous bulb oxygen saturation in the unconscious patient.
复制标题
在昏迷患者中使用间歇和连续记录颈静脉球氧饱和度。
DOI：
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发表时间：
1987
期刊：
影响因子：
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通讯作者：
D. Bihari
中科院分区：
文献类型：
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作者：
R. Garlick;D. Bihari
监测无意识患者的临床体征只能提供有关大脑恶化的晚期信息。缺血和缺氧是大部分损伤的机制。脑血流量（CBF）的测量提供了缺血的直接证据，但可能是一个不稳定的情况下间歇值。连续记录CBF和氧合比间歇性读数更可能在早期揭示缺血和缺氧的有害趋势。我们报告我们的经验，间歇性和连续记录颈静脉球血氧饱和度（JVO2Sat）获得的光纤血氧饱和度在一组10个头部受伤和7个脓毒症患者。同时测量CBF的同位素氙清除法也进行了。JVO2Sat已被认为是脑氧合的可靠指标，低值指示缺血。我们讨论我们的研究结果是否支持这一说法。JVO2Sat也随平均动脉压和颅内压而变化。这些变化在解释JVO2Sat的一个单一值时具有重要意义。
Monitoring clinical signs in unconscious patients provides only late information about cerebral deterioration. Ischaemia and hypoxia are the mechanisms of much of the damage. Cerebral blood flow (CBF) measurements provide direct evidence of ischaemia but are intermittent values for what may be an unstable situation. Continuous recordings of CBF and oxygenation are more likely to reveal harmful tendencies to ischaemia and hypoxia at an early stage than intermittent readings. We report our experience with intermittent and also continuous recording of the jugular venous bulb oxygen saturation (JVO2Sat) obtained by fibreoptic oximetry in a group of 10 head injured and 7 septic patients. Simultaneous measurements of CBF by an isotopic xenon clearance method were also made. The JVO2Sat has been suggested to be a reliable indicator of cerebral oxygenation, a low value being indicative of ischaemia. We discuss whether our findings support this statement. There are also variations in JVO2Sat with mean arterial blood pressure and intracranial pressure. These variations have important implications in the interpretation that can be made of one single value of JVO2Sat.