Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer.
Blockade of the PD-1 pathway enhances the efficacy of adoptive cell therapy against cancer.
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DOI:
10.4161/onci.22691
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发表时间:
2013-02-01
期刊:
影响因子:
7.2
通讯作者:
Hwu P
中科院分区:
文献类型:
--
作者:
Peng W;Lizée G;Hwu P
The blockade of the PD-1 pathway can increase the production of interferon γ by tumor-specific T cells located within or in the proximity of the malignant lesion, thereby increasing the chemokine-dependent trafficking of immune effector cells. This can boost the efficacy of adoptive T-cell therapy to achieve superior antitumor responses.
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影响因子:
11.2
作者:
Peng W;Liu C;Xu C;Lou Y;Chen J;Yang Y;Yagita H;Overwijk WW;Lizée G;Radvanyi L;Hwu P
通讯作者:
Hwu P
DOI:
10.1038/nri3191
发表时间:
2012-03-22
期刊:
Nature reviews. Immunology
影响因子:
--
作者:
Restifo NP;Dudley ME;Rosenberg SA
通讯作者:
Rosenberg SA
影响因子:
17.1
作者:
Taube JM;Anders RA;Young GD;Xu H;Sharma R;McMiller TL;Chen S;Klein AP;Pardoll DM;Topalian SL;Chen L
通讯作者:
Chen L
DOI:
10.1056/nejmoa1200694
发表时间:
2012-06-28
期刊:
The New England journal of medicine
影响因子:
--
作者:
Brahmer JR;Tykodi SS;Chow LQ;Hwu WJ;Topalian SL;Hwu P;Drake CG;Camacho LH;Kauh J;Odunsi K;Pitot HC;Hamid O;Bhatia S;Martins R;Eaton K;Chen S;Salay TM;Alaparthy S;Grosso JF;Korman AJ;Parker SM;Agrawal S;Goldberg SM;Pardoll DM;Gupta A;Wigginton JM
通讯作者:
Wigginton JM
影响因子:
2.8
作者:
Chen, Jiao;Feng, Yun;Zhang, Ping
通讯作者:
Zhang, Ping