Age- and sex-specific effects on weight loss outcomes in a comparison of sleeve gastrectomy and Roux-en-Y gastric bypass: a retrospective cohort study.
Age- and sex-specific effects on weight loss outcomes in a comparison of sleeve gastrectomy and Roux-en-Y gastric bypass: a retrospective cohort study.
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DOI：
10.1186/2052-9538-1-12
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发表时间：
2014-01-01
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影响因子：
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通讯作者：
Batterham, Rachel L
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文献类型：
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作者：
Manning, Sean;Carter, Nicholas C;Batterham, Rachel L
BACKGROUND: Roux-en-Y gastric bypass (RYGBP) and sleeve gastrectomy (SG) are the most common bariatric procedures undertaken globally but there are no evidenced-based criteria that inform the selection of one operation over the other. The purpose of this study was thus to compare weight loss outcomes between RYGBP and SG, and to define patient factors affecting weight loss.METHODS: A single-centre two-year follow-up retrospective cohort study of all adults who underwent either RYGBP (n=422) or SG (n=432) between 2007 and 2012, at University College London Hospitals National Health Service Foundation Trust, an academic tertiary referral centre, was undertaken. Multilevel linear regression was used to compare weight loss between groups, enabling adjustment for preoperative BMI (body mass index) and evaluation for interaction factors.RESULTS: One- and two-year results showed that unadjusted BMI loss was similar between groups; 13.7kg/m(2) (95% CI: 12.9, 14.6kg/m(2)) and 12.8kg/m(2) (95% CI: 11.8, 13.9kg/m(2)) for RYGBP patients respectively compared with 13.3kg/m(2) (95% CI: 12.0, 14.6kg/m(2)) and 11.5kg/m(2) (95% CI: 10.1, 13.0kg/m(2)) for SG patients respectively. Adjusting for preoperative BMI, there was 2.2kg/m(2) (95% CI: 1.5, 2.8) and 2.3kg/m(2) (95% CI: 1.3, 3.3) greater BMI loss in the RYGBP group compared to the SG group at one and two years respectively (P
