The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology.

The Mouse Genome Database (MGD): from genes to mice--a community resource for mouse biology.
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DOI:
10.1093/nar/gki113
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发表时间:
2005-01-01
影响因子:
14.9
通讯作者:
Mouse Genome Database Group
Mouse Genome Database Group
中科院分区:
生物学2区
文献类型:
--
作者:
Eppig JT;Bult CJ;Kadin JA;Richardson JE;Blake JA;Anagnostopoulos A;Baldarelli RM;Baya M;Beal JS;Bello SM;Boddy WJ;Bradt DW;Burkart DL;Butler NE;Campbell J;Cassell MA;Corbani LE;Cousins SL;Dahmen DJ;Dene H;Diehl AD;Drabkin HJ;Frazer KS;Frost P;Glass LH;Goldsmith CW;Grant PL;Lennon-Pierce M;Lewis J;Lu I;Maltais LJ;McAndrews-Hill M;McClellan L;Miers DB;Miller LA;Ni L;Ormsby JE;Qi D;Reddy TB;Reed DJ;Richards-Smith B;Shaw DR;Sinclair R;Smith CL;Szauter P;Walker MB;Walton DO;Washburn LL;Witham IT;Zhu Y;Mouse Genome Database Group

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小鼠基因组数据库(MGD)是小鼠基因组信息学(MGI)系统(http://www.example.com)的核心,是实验室小鼠的模式生物数据库资源。www.informatics.jax.org MGD为小鼠系统提供了必要的实验知识整合,并从文献和在线资源中注释了信息。MGD通过表型信息策划和呈现基因型(序列)的共识和实验数据表示,包括关于基因和基因产物的高度详细的报告。整合的主要焦点是通过表达基因、序列和表型之间的关系。MGD与其他生物信息学小组合作,策划一套关于实验室小鼠的明确信息,并建立和实施对比较基因组分析至关重要的数据和语义标准。本文讨论了MGD的最新进展,包括表型资源的增强,国际小鼠品系资源(IMSR)的重新开发,哺乳动物直系数据集的更新和小鼠遗传学经典书籍的电子出版。
The Mouse Genome Database (MGD) forms the core of the Mouse Genome Informatics (MGI) system (http://www.informatics.jax.org), a model organism database resource for the laboratory mouse. MGD provides essential integration of experimental knowledge for the mouse system with information annotated from both literature and online sources. MGD curates and presents consensus and experimental data representations of genotype (sequence) through phenotype information, including highly detailed reports about genes and gene products. Primary foci of integration are through representations of relationships among genes, sequences and phenotypes. MGD collaborates with other bioinformatics groups to curate a definitive set of information about the laboratory mouse and to build and implement the data and semantic standards that are essential for comparative genome analysis. Recent improvements in MGD discussed here include the enhancement of phenotype resources, the re-development of the International Mouse Strain Resource, IMSR, the update of mammalian orthology datasets and the electronic publication of classic books in mouse genetics.
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