ENDOCRINE CORRELATES OF STRESS VULNERABILITY
ENDOCRINE CORRELATES OF STRESS VULNERABILITY
复制标题
DOI：
10.1159/000288675
复制
发表时间：
1993-01-01
影响因子：
22.8
通讯作者：
WADE, S
中科院分区：
文献类型：
--
作者：
HELLHAMMER, DH;WADE, S
心理压力被认为是心身疾病发展和维持的一系列危险因素中的一个因素。个体对压力经历的内分泌反应差异很大，这可能解释了在压力下对心身症状发展的易感性的个体差异。内分泌应激反应可能有很大的遗传成分，但也被认为是可以通过长期和/或深刻的压力经历来改变的。社会和认知因素影响垂体-肾上腺对压力的反应，性别差异也可能显著。也许有可能制定内分泌反应性的具体测试，也许包括心理和药理学挑战，这可能作为慢性压力经历或易患心身疾病的标志。
Psychological stress is implicated as one element in a constellation of risk factors for the development and maintenance of psychosomatic disease. Endocrine responses to stressful experience vary widely among individuals, and may account for some of the individual variability in vulnerability to development of psychosomatic symptoms under stress. Endocrine stress responsiveness probably has a large genetic component, but is also known to be modifiable by prolonged and/or profound stressful experience. Social and cognitive factors influence the pituitary-adrenal response to stress, and sex differences may also be significant. It may be possible to develop specific tests of endocrine responsiveness, perhaps incorporating psychological and pharmacological challenges, that may serve as markers of chronic stress experience or of vulnerability to psychosomatic disorders.