Base pair analogs in the gas phase
Base pair analogs in the gas phase
复制标题
DOI：
10.1073/pnas.2333806100
复制
发表时间：
2003-11-25
影响因子：
11.1
通讯作者：
Pratt, DW
中科院分区：
文献类型：
--
作者：
Roscioli, JR;Pratt, DW
A rotationally resolved electronic spectrum of the gas-phase dimer 2-aminopyridine-2-pyridone, an analog of the adenine-thymine base pair, has been observed and assigned, leading to precise measurements of its moments of inertia and preliminary determinations of its structure. A Watson-Crick configuration results, with N...H-N and N-H...O hydrogen bond lengths of 2.898 and 2.81o Angstrom, respectively. The two bases are found not to be coplanar; a dihedral angle of 6.1degrees between the base planes is also estimated from the measured moments of inertia. Possible chemical and biological implications of these results are discussed.
